Publikationen

Publikationen 2022

  • L. Bachmann, L. Gallego Villarejo, N. Heinen, D. Marks, M. Peters, and T. Müller (2022).
    Gene-edited fluorescent and mixed cerebral organoids.
    The CRISPR Journal .
    doi: 10.1089/crispr.2021.0070
    Abstract
     

Publikationen 2021

  • M. Bormann, M. Alt, L. Schipper, L. van de Sand, V.T.K. Le-Trilling, L. Rink, N. Heinen, R.J. Madel, M. Otte, K. Wuensch, C.S. Heilingloh, T. Mueller, U. Dittmer, C. Elsner, S. Pfaender, M. Trilling, O. Witzke, and A. Krawczyk (2021).
    Turmeric root and its bioactive ingredient curcumin effectively neutralize SARS-CoV-2 in vitro.
    Viruses 13(10): 1914.
    doi: 10.3390/v13101914
    Abstract
     
  • Y. Yao, S.S. Kang, Y. Xia, Z.-H. Wang, X. Liu, T. Müller, Y. E Sun, and K. Ye (2021).
    A delta-secretase-truncated APP fragment activates CEBPB, mediating Alzheimers disease pathologies.
    Brain 144(6): 1833–1852.
    doi: 10.1093/brain/awab062
    Abstract
     
  • D. Marks, N. Heinen, L. Bachmann, S. Meermeyer, M. Werner, L. Gallego, P. Hemmerich, V. Bader, K.F. Winklhofer, E. Schröder, S.K. Knauer, and T. Müller (2021).
    Amyloid precursor protein elevates fusion of promyelocytic leukemia nuclear bodies in human hippocampal areas with high plaque load.
    Acta Neuropathologica Communications 9: 66
    doi: 10.1186/s40478-021-01174-x
    Abstract
     

Publikationen 2020

  • C.D. Pereira, F. Martins, M. Santos, T. Müller, O.A.B. da Cruz e Silva, S. Rebelo (2020).
    Nuclear accumulation of LAP1: TRF2 complex during DNA damage response uncovers a novel role for LAP1.
    Cells 9(8): 1804.
    doi: 10.3390/cells9081804
    Abstract
     

Publikationen 2019

  • J. Scott, …, T. Müller, …, and F. Bellivier (2019).
    Prospective cohort study of early biosignatures of response to lithium in bipolar-I-disorders: overview of the H2020-funded R-LiNK initiative.
    International Journal of Bipolar Disorders 7(1): 20.
    doi: 10.1186/s40345-019-0156-x
    Abstract
     

Publikationen 2018

  • A.L. Comes, S. Papiol, T. Müller, P.E. Geyer, M. Mann, and T.G. Schulze (2018).
    Proteomics for blood biomarker exploration of severe mental illness: pitfalls of the past and potential for the future.
    Translational Psychiatry 8: 160.
    doi: 10.1038/s41398-018-0219-2
    Abstract
     
  • F. Martins, A.M. Marafona, C.D. Pereira, T. Müller, C. Loosse, K. Kolbe, O.A.B. da Cruz e Silva, and S. Rebelo (2018).
    Identification and characterization of the BRI2 interactome in the brain.
    Scientific Reports 8: 3548.
    doi: 10.1038/s41598-018-21453-3
    Abstract
     

Publikationen 2017

  • J.M. Oliveira, C.B. da Cruz e Silva, T. Müller, T.S. Martins, M. Cova, O.A.B. da Cruz e Silva, and A.G. Henriques (2017).
    Toward neuroproteomics in biological psychiatry: a systems approach unravels okadaic acid-induced alterations in the neuronal phosphoproteome.
    OMICS 21(9): 550–563.
    doi: 10.1089/omi.2017.0108
    Abstract
     
  • H. Bukhari, A. Glotzbach, K. Kolbe, G. Leonhardt, C. Loosse, and T. Müller (2017).
    Small things matter: Implications of APP intracellular domain AICD nuclear signaling in the progression and pathogenesis of Alzheimer's disease.
    Progress in Neurobiology 156: 189–213.
    doi: 10.1016/j.pneurobio.2017.05.005
    Abstract
     
  • F. Martins, J.B.Serrano, T. Müller, O.A.B. da Cruz e Silva, and Sandra Rebelo (2017).
    BRI2 processing and its neuritogenic role are modulated by protein phosphatase 1 complexing.
    Journal of Cellular Biochemistry 118(9): 2752–2763.
    doi: 10.1002/jcb.25925
    Abstract
     
  • A. Schrötter, A. Oberhaus, K. Kolbe, S. Seger, T. Mastalski, F. El Magraoui, E. Hoffmann-Posorske, M. Bohnert, J. Deckert, C. Braun, M. Graw, C. Schmitz, T. Arzberger, C. Loosse, H. Heinsen, H.E. Meyer, and T. Müller (2017).
    LMD proteomics provides evidence for hippocampus field-specific motor protein abundance changes with relevance to Alzheimer's disease.
    Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1865(6): 703–714.
    doi: 10.1016/j.bbapap.2017.03.013
    Abstract
     

Publikationen 2016

  • K. Kolbe, H. Bukhari, C. Loosse, G. Leonhardt, A. Glotzbach, M. Pawlas, K. Hess, C. Theiss, and T. Müller (2016).
    Extensive nuclear sphere generation in the human Alzheimer's brain.
    Neurobiology of Aging 48: 103–113.
    doi: 10.1016/j.neurobiolaging.2016.08.016
    Abstract
     
  • H. Bukhari, K. Kolbe, G. Leonhardt, C. Loosse, E. Schröder, S. Knauer, K. Marcus, and T. Müller (2016).
    Membrane tethering of APP c-terminal fragments is a prerequisite for T668 phosphorylation preventing nuclear sphere generation.
    Cellular Signalling 28(11): 1725–1734.
    doi: 10.1016/j.cellsig.2016.08.007
    Abstract
     
  • A.G. Henriques, T. Müller, J.M. Oliveira, M. Cova, C.B. da Cruz e Silva, O.A.B. da Cruz e Silva (2016).
    Altered protein phosphorylation as a resource for potential AD biomarkers.
    Scientific Reports 6: 30319.
    doi: 10.1038/srep30319
    Abstract
     
  • C. Loosse, M. Pawlas, H.S.S. Bukhari, A. Maghnouj, S. Hahn, K. Marcus, and T. Müller (2016).
    Nuclear spheres modulate the expression of BEST1 and GADD45G.
    Cellular Signalling 28(1): 100–109.
    doi: 10.1016/j.cellsig.2015.10.019
    Abstract
     

Publikationen 2015

  • C. Looße, S. Galozzi, L. Debor, M.K. Julsing, B. Bühler, A. Schmid, K. Barkovits, T. Müller, and K. Marcus (2015).
    Direct infusion-SIM as fast and robust method for absolute protein quantification in complex samples.
    EuPA Open Proteomics 7: 20–26.
    doi: 10.1016/j.euprot.2015.03.001
    Abstract
     

Publikationen 2014

  • M. Santos, S.C. Domingues, P. Costa, T. Müller, S. Galozzi, K. Marcus, E.F. da Cruz e Silva, O.A. da Cruz e Silva, S. Rebelo (2014).
    Identification of a novel human LAP1 isoform that is regulated by protein phosphorylation.
    PLoS ONE 9(12): e113732.
    doi: 10.1371/journal.pone.0113732
    Abstract
     
  • F. El Magraoui, A. Schrötter, R. Brinkmeier, L. Kunst, T. Mastalski, T. Müller, K. Marcus, H.E. Meyer, W. Girzalsky, R. Erdmann , H.W. Platta (2014).
    The cytosolic domain of Pex22p stimulates the Pex4p-dependent ubiquitination of the PTS1-receptor.
    PLoS ONE 9(8): e105894.
    doi: 10.1371/journal.pone.0105894
    Abstract
     
  • F.M. Nensa, M.H.D. Neumann, A. Schrötter, A. Przyborski, T. Mastalski, S. Susdalzew, C. Looße, S. Helling, F. El Magraoui, R. Erdmann, H.E. Meyer, J. Uszkoreit, M. Eisenacher, J. Suh, S.Y. Guénette, N. Röhner, D. Kögel, C. Theiss, K. Marcus, and T. Müller (2014).
    Amyloid beta A4 precursor protein-binding family B member 1 (FE65) interactomics revealed synaptic vesicle glycoprotein 2A (SV2A) and sarcoplasmic/endoplasmic reticulum calcium ATPase 2 (SERCA2) as new binding proteins in the human brain.
    Molecular and Cellular Proteomics 13: 475–488.
    doi: 10.1074/mcp.M113.029280
    Abstract
     

Publikationen 2013

  • A. Schrötter, T. Mastalski, F.M. Nensa, M. Neumann, C. Loosse, K. Pfeiffer, F. El Magraoui, H.W. Platta, R. Erdmann, C. Theiss, J. Uszkoreit, M. Eisenacher, H.E. Meyer, K. Marcus, and T. Müller (2013).
    FE65 regulates and interacts with the Bloom syndrome protein in dynamic nuclear spheres – potential relevance to Alzheimer’s disease.
    Journal of Cell Science 126: 2480–2492.
    doi: 10.1242/jcs.121004
    Abstract
     
  • T. Müller, A. Schrötter, C. Loosse, K. Pfeiffer, C. Theiss, M. Kauth, H.E. Meyer, and K. Marcus (2013).
    A ternary complex consisting of AICD, FE65, and TIP60 down-regulates Stathmin1.
    Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 1834(1): 387–394.
    doi: 10.1016/j.bbapap.2012.07.017
    Abstract
     

Publikationen 2008

  • T. Müller, H.E. Meyer, R. Egensperger, and K. Marcus (2008).
    The amyloid precursor protein intracellular domain (AICD) as modulator of gene expression, apoptosis, and cytoskeletal dynamics—Relevance for Alzheimer's disease.
    Progress in Neurobiology 85(4): 393–406.
    doi: 10.1016/j.pneurobio.2008.05.002
    Abstract
     

Publikationen 2007

  • T. Müller, C.G. Concannon, M.W. Ward, C.M. Walsh, A.L. Tirniceriu, F. Tribl, D. Kögel, J.H.M. Prehn, and R. Egensperger (2007).
    Modulation of gene expression and cytoskeletal dynamics by the amyloid precursor protein intracellular domain (AICD).
    Molecular Biology of the Cell 18(1): 201–210.
    doi: 10.1091/mbc.E06-04-0283
    Abstract
     

Bücher

Publikation des Jahres