Applied Methods

Methods Faculty Members
Acute brain slices Eysel, Manahan-Vaughan, Masseck, Prochnow
Animal behaviour Masseck
Animal models of brain disease Krieger, Masseck
Animal models of retinal/optic nerve diseases Joachim
Adenoviral expression system Heumann
Analysis of walking in rats Dinse
Animal behaviorals pardigms Juckel
Applied computer science Würtz
Artificial brain stimulation (TMS, ICMS) Funke, Nitsche
Behavioral analysis of learning Krieger
Behavioral studies with PCD-controlled skinner boxes, lesion studies, pharmacology of behavior Güntürkün, Manns
Behavioural studies of hippocampus-dependent learning Manahan-Vaughan
Biobanking Epplen
Biochemistry of the extracellular matrix and complementary receptors Faissner
Bioluminescence imaging Kleiter
Biomolecular chip technologies Lübbert
Brain mapping Nitsche
Calcium imaging Hollmann, Reiner
Cell implantation Lübbert
Cerebellar recordings Kruse
Cerebellar slice cultures Theiss
Coactivated-induced perceptual learning Dinse
Computational modeling Cheng, Ebbinghaus, Nitsche, Schöner, Werning, Wiskott, Würtz
Computer vision Würtz
Conceptual Analysis Werning
Confocal microscopy, video microscopy Ebbinghaus, Faissner, Funke, Hollmann, Masseck
Confocal laser scanning microscopy Funke, Theiss
Cytogenetics Epplen
DNA arrays Epplen
DNA diagnostics Epplen
DNA fingerprinting Epplen
DNA methylation analysis Kumsta
DNA sequencing Epplen
Data mining Cheng
Deep brain stimulation Axmacher, Nitsche
Development of bioassays for the analysis of the growth of neurites Faissner
Diffusion Tensor Imaging (DTI) Schmidt-Wilcke, Weigelt
Digitial image processing Ebbinghaus
Dissociated primary cultures Faissner, Heumann, Hollmann, Lübbert, Wiese
EBV transfection Epplen
Electroencephalogram (EEG), human Axmacher, Bellebaum, Nitsche, Werning, Wolf
Electroencephalogram (EEG), rodent Manahan-Vaughan
Electromyography (EMG) Brüne, Nitsche
Electroretinography (ERG) Joachim
Electron microscopy Theiss
Electron microscopy, immuno-EM Lübbert
Electrophysiology Juckel, Masseck, Prochnow, Reiner
Electrophysiology and biochemistry in frog oocytes Hollmann
Electrophysiology of synaptic plasticity Manahan-Vaughan, Prochnow
Enriched environmental conditions Dinse, Funke, Manahan-Vaughan
Event related potentials (ERPs) Nitsche, Suchan
Evoked potentials (EP) Brüne, Nitsche
Expression of recombinant proteins in bacteria and mammalian cells Ebbinghaus, Heumann, Hollmann, Reiner, Wiese
Fast Relaxation Imaging Ebbinghaus
Functional Magnetic Resonance Imaging (fMRI) Axmacher, Brüne, Schmidt-Wilcke, Suchan, Tegenthoff, Weigelt
Gene-Environment Interaction Kumsta
Histology Juckel
HPLC (High Performance Liquid Chromatography) Funke
Human movement laboratory Schöner
ICMS (Intracortical Micro-stimulation) Dinse, Funke
Imaging techniques (two photon microscopy, TIRF, FLIM, FRET, FRAP, BiFC) Ebbinghaus, Herlitze, Reiner
Immuncytochemistry Juckel, Winklhofer
Immunohistochemistry and histology Dietzel-Meyer, Funke, Güntürkün, Heumann, Joachim, Kleiter, Lübbert, Manns, Prochnow, Tatzelt, Theiss, Wiese
Immunopanning techniques Wiese
In-situ hybridisidation, combination with immunohistochemistry or tract-tracing Lübbert
Indirect immunofluorescence Tatzelt
In-vivo microdialysis Funke, Güntürkün
Intra- and extracellular measurements, ion-sensitive
micro-electrodes, patch clamp measurements of glial cells and neurons
Intracellular measurements with sharp electrodes Eysel
Intracranial EEG Axmacher
Intraocular pressure measurements (IOP) Joachim
Learning and memory in humans Nitsche
Lesions in the brain (by laser, drugs, photothrombosis) Eysel, Lübbert
Lesions in the brain (mechanically induced) Prochnow
Logics Werning
Manufacturing of recombinant antibodies Heumann
Mathematical modeling Cheng, Ebbinghaus, Reiner, Schöner, Würtz
Mathematics Schöner, Werning, Wiskott
Measurements of salivary sex-steroid hormones Güntürkün, Wolf
Measurement of reaction times Dinse, Nitsche, Weigelt, Wolf
Measurement of the peripheral conductance velocity of nerve cells Schmidt-Wilcke, Schwenkreis, Tegenthoff
Measurements of salivary sex-steroid hormones Kumsta
Measurements of salivary stress markers Kumsta, Wolf
Microdialysis Juckel
Micro-injection techniques (proteins, DNA, etc.) Funke, Heumann, Hollmann, Lübbert, Theiss
Models of experimental demyelination Kleiter
Model-based analysis of neural and behavioral data Cheng
Molecular cloning, expression cloning, cDNA Banks,
Ebbinghaus, Faissner, Epplen, Heumann, Hollmann, Lübbert, Reiner
Molecular genetics Kumsta
Monoclonal antibodies Faissner
Motor cortex mapping Dinse
Mouse genetics (transgene expression and homologous recombination) Herlitze, Wiese
Multi-channel electrophysiology in humans, brain mapping, source localisation Nitsche, Schwenkreis, Tegenthoff
Multi-colour neuronal tract tracing Güntürkün, Manns
Multi-electrode recordings in rodents Kruse
Multiphoton confocal microscopy Krieger, Masseck
Multivariate pattern classification analysis (MVPA) Axmacher
Neuronal stem cell culture Kleiter
Optical coherence tomography (OCT) Joachim
Optical imaging in vivo Krieger
Optical recording of intrinsic signals Dinse, Eysel, Funke, Jancke
Optogenetics Krieger, Masseck, Reiner
Patch clamp Krieger
Patch clamp measurements in cultured cells and slice preparations Herlitze, Masseck, Prochnow, Reiner
Patch clamp ("blind" patch, infrared video microscopy) Eysel, Hollmann, Prochnow
PC-based reconstruction of neurons, morphometry Eysel, Funke, Güntürkün
PC-based studies of attention, learning and memory in humans Nitsche, Weigelt, Wolf
PC-based studies of vision, audition and multisensory stimulation Weigelt
PCR, RT-PCR Ebbinghaus, Epplen, Faissner, Heumann, Hollmann, Kumsta, Tatzelt, Wiese, Winklhofer
PCR-mutagenesis (mutations, chimaera) Ebbinghaus, Heumann, Hollmann
Pediatric neuroimaging Weigelt
Pharmacological manipulation in humans Dinse, Nitsche, Tegenthoff, Wolf
Population coding in visual cortex Jancke
Posttranslational protein modifications (phosphorylation, ubiquitination, sumoylation) Winklhofer
Primary culture of dissociated neuronal and glial cells Theiss, Wiese, Winklhofer
Primary culture of embryonic motor neurons Wiese
Primary cultures and cell lines Heumann, Lübbert, Tatzelt, Winklhofer
Primary organ culture of retinal explants Joachim
Protein biochemistry, Western Blots Ebbinghaus, Funke, Heumann, Hollmann, Joachim, Lübbert, Reiner, Tatzelt, Winklhofer
Protein chromatography Reiner, Tatzelt, Winklhofer
Protein protein interactions: phage display, blot overlay,
co-immunoprecipitation, pulldown, biacore
Proteomics analysis in purified parts of the nervous system and neuroblastoma cell lines Heumann
Psychophysics Dinse, Weigelt
Psychophysics of finger-hand motorics Dinse
Psychophysiological measurements Weigelt, Wolf
Psychophysiology (e.g. facial expression analysis) Juckel
Real-time optical imaging of the visualcortex using voltage-sensitive dyes in parallel with extracellular recordings Jancke
Recombinant protein expression in E. coli Reiner, Tatzelt, Winklhofer
Registration of synaptic currents after fast application of transmitters Hollmann
Retrograde and anterograde axonal tract tracing in vivo + target directed recordings of labeled neurons in vitro Prochnow
RNA analysis (differential splicing) Epplen
Robotics Schöner
Rodent learning paradigms (water maze, radial maze, operant chamber) Funke
Scanning ion-conductance microscopy Dietzel-Meyer
Simultaneous EEG/fMRI Axmacher
Single cell labelling with Biocytin Eysel
Single cell RT-PCR Hollmann
Single-cell electrophysiology in awake, learning and anesthetized pigeons Güntürkün
Single-cell electrophysiology of the visual and somato-sensory cortex Dinse, Funke
Single channel recordings in vitro (inside out, outside out, cell attached) Prochnow, Reiner
Skin conductance (electrodermal activity, EDA) Axmacher, Brüne
Social cognition Brüne, Weigelt
Source localisation Nitsche
Spectroscopy Reiner, Schmidt-Wilcke
Stereology Manns
Stereotactic tracer injections Güntürkün, Lübbert, Manns
Stress induction in the laboratory Kumsta, Wolf
Structural Magnetic Resonance Imaging (sMRI) Axmacher, Juckel
Study of nonverbal behaviour Brüne
TMS (Transcraniel Magnetic Stimulation) Brüne, Funke, Nitsche, Schwenkreis, Tegenthoff
Tactile psychophysics Dinse
Transfection techniques Heumann, Winklhofer
Transgenic animals Epplen, Heumann, Kleiter, Lübbert
Transgenic mouse models Krieger
Two electrode patch clamp Hollmann
Video microscopy Theiss
Virus-mediated infection methods (Sindbis virus) Herlitze, Masseck
Visual psychophysics Dinse, Weigelt
Visual half-field studies in humans Güntürkün
Whole cell-measurements in vitro, DIC Microscopy Ebbinghaus, Eysel
Yeast-2-Hybrid System Heumann