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Optogenetics

Prof. Dr. Stefan Herlitze, Dr. Wolfgang Kruse, Dr. Ida Siveke, Dr. Katharina Spoida,
Brix Mücher, Bianca Preissing, Lennard Rohr, Tatjana Surdin

 

Optogenetics is a new technique, where light activated proteins derived from bacteria, algae, plants or animals are expressed in for example neuron of the mouse brain. The goal of this techniques is to switch on and off signaling cascades with high temporal and spatial resolution using light in specific types of cells and cellular compartments. We are using in particular vertebrate opsins of the human and mouse retina, to control GPCR signals to understand the function of the GPCR signals to elicit and modulate mouse behavior.

The Bochum research team: Bianca Preissing, Lennard Rohr, Ida Siveke and Tatjana Surdin (from left) (RUB News)