Publikationen

2016

A family of photoswitchable NMDA receptors.
Berlin S.*/Szobota S.*, Reiner A., Carroll E.C., Kienzler M.A., Guyon A., Xiao T., Trauner D. & Isacoff, E.Y.. eLife (2016): 5:e12040.

A toolkit for orthogonal and in vivo optical manipulation of ionotropic glutamate receptors.
Levitz J.*/Popescu A.T.*/Reiner A.* & Isacoff, E.Y.. Front. Mol. Neurosci. (2016): 00002.

Book Chapter: Optogenetics.
Isacoff E.Y. & Reiner A.. In Encyclopedia of Cell Biology (ed. Bradshaw R.A., Stahl P.D.), Elsevier, Amsterdam.
Encyclopedia of Cell Biology, Vol. 2 (2016): 147-155.

2015

Review: Controlling ionotropic and metabotropic glutamate receptors with light: principles and potential.
Reiner A.*/Levitz J.* & Isacoff, E.Y.. Curr. Opin. Pharm. 20 (2015): 135-143.

2014

Restoration of visual function by expression of a light-gated mammalian ion channel in retinal ganglion cells or ON-bipolar cells.
Gaub B.M.*/ Berry M.H.*, Holt A.E., Reiner A., Kienzler M.A., Dolgova N., Nikonov S., Aguirre G.D., Beltran W.A., Flannery J. & Isacoff E.Y.. Proc. Natl. Acad. Sci. USA 111 (2014): E5574-5583.

Long wavelength optical control of glutamate receptor ion channels using a tetra-ortho-substituted azobenzene.
Rullo A.*/Reiner A.*, Reiter A., Trauner D., Isacoff E.Y. & Woolley G.A.. Chem. Comm. 50 (2014): 14613-14615.

Tethered ligands reveal glutamate receptor desensitization depends on subunit occupancy.
Reiner A. & Isacoff E.Y.. Nat. Chem. Biol. 10 (2014): 273-280.

Book Chapter: Photoswitching of cell-surface receptors using tethered ligands.
Reiner A. & Isacoff E.Y.. In Photoswitching Proteins: Methods and Protocols (ed. Cambridge S.), Humana Press, New York.
Meth. Mol. Biol. 1148 (2014): 45-68.

2013

A red-shifted, fast-relaxing azobenzene photoswitch for visible light control of an ionotropic glutamate receptor.
Kienzler M.A.*/Reiner A.*, Trautman E., Yoo S., Trauner D. & Isacoff E.Y.. J. Am. Chem. Soc. 135 (2013): 17683-17686.

Optical control of metabotropic glutamate receptors.
Levitz J., Pantoja C., Gaub B., Janovjak H., Reiner A., Hoagland A., Schoppik D., Kane B., Stawski P., Schier A.F., Trauner D. & Isacoff E.Y.. Nat. Neurosci. 16 (2013): 507-516.

Testing the diffusing boundary model for the helix-coil transition in peptides.
Neumaier S., Reiner A., Büttner M., Fierz, B. & Kiefhaber T.. Proc. Natl. Acad. Sci. USA 110 (2013): 12905-12910.

Minireview: The Brain Prize 2013: The optogenetics revolution.
Reiner A. & Isacoff E.Y.. Trends Neurosci. 35 (2013): 557-560.

Perspective: Bringing optogenetics to the synapse.
Reiner A. & Isacoff E.Y.. Neuron 79 (2013): 209-210.

2012

Assembly stoichiometry of the GluK2/GluK5 kainate receptor complex.
Reiner A., Arant R.J. & Isacoff E.Y.. Cell Rep. 1 (2012): 234-240.

2010/2011

Minireview: Triplet-triplet energy transfer studies on conformational dynamics in peptides and a protein.
Reiner A.. J. Pep. Sci. 17 (2011): 413-419.

Book Chapter: Conformational dynamics in peptides and proteins studied by triplet-triplet energy transfer.
Reiner A., Fierz B. & Kiefhaber T.. In Methods of Protein Biochemistry (ed. Tschesche H.), Walter de Gruyter, Berlin (2011): 73-94.

A reversible unlocking/relocking barrier in conformational fluctuations of villin headpiece subdomain.
Reiner A., Henklein P. & Kiefhaber T.. Proc. Natl. Acad. Sci. USA 107 (2010): 4955-4960.

2008/2009

Local conformational dynamics in α-helices measured by fast triplet transfer.
Fierz B.*/Reiner A.* & Kiefhaber T.. Proc. Natl. Acad. Sci. USA 106 (2009): 1057-1062.

NMR structure of a monomeric intermediate on the evolutionarily optimized assembly pathway of a small trimerization domain.
Habazettl J., Reiner A. & Kiefhaber T.. J. Mol. Biol. 389 (2009): 103-114.

Effect of thioxopeptide bonds on α-helix structure and stability.
Reiner A., Wildemann D., Fischer G. & Kiefhaber T.. J. Am. Chem. Soc. 130 (2008): 8079-8084.