Junior Prof Dr Andreas Reiner

Juniorprof. Dr. Andreas Reiner
NG Cellular Neurobiology
Faculty of Biology and Biotechnology

  • Dr. Andreas Reiner
  • Ruhr University Bochum
    Bldg./Room: ND 5/29
    Universitätsstrasse 150
    44801 Bochum
    Germany
  • Tel:  +49 (0)234 32-24332
    Fax: +49 (0)234 32-04332
  • andreas.reiner@rub.de
  • How to get there

Research Department of Neuroscience

International Graduate School of Neuroscience (IGSN)

We gratefully acknowledge support from the
Ministerium für Innovation, Wissenschaft und Forschung des Landes Nordrhein-Westfalen

Optical Control and Probing of Synaptic Signaling Proteins

We use novel, optical approaches to study membrane proteins, in particular to understand how protein complexes assemble and transmit signals across cell membranes.

Our main focus is on glutamate receptor signaling. Glutamate receptors (GluRs) play a key role in the central nervous system, where they pass excitatory signals across synapses and modulate synaptic strength and plasticity.

We combine biochemical methods, spectroscopic techniques, live cell imaging and electrophysiology to gain further insight into GluR function and physiology. As part of our toolset we use chemical photoswitches to manipulate GluRs with light – a method that allows for the precise control of specific receptor complexes with high spatial and temporal precision. At the same time, the engineering of photo-controllable ion channels and GPCRs provides a powerful tool for optogenetic and pharmacological studies.