Coming soon: Talks by Prof. Dr. Paolo Carloni and Dr. Sandra Diaz (Forschungszentrum Jülich)

Date and time: tba

Talk by Prof. Dr. Paolo Carloni about: Multiscale simulations of key molecular events at the synapsis

Abstract: To understand how drugs affect the brain and how diseases impact the central nervoussystem, we need to uncover the principles of chemical neurotransmission. Here, I will describe our efforts to describe molecular processes at the synapse using computer simulations at different levels (from quantum to coarse-grain), aided by machine learning approaches. I will conclude the talk by discussing possible connections between biomolecular and neuronal simulations.

Talk by Dr. Sandra Diaz about: Using high performance computing to optimize brain models across scales

Abstract: Scientists use mathematical models to study the brain at different spatial and temporal scales, from the molecular level to the whole brain, from ion channel dynamics to cognitive function. These mathematical models are usually highly under-constrained and optimization their parameters is required to make them fit experimental observations and produce useful insight. In this talk I will present a set of scientific use cases where we have used scalable methods on high performance computing systems to optimize models in neuroscience research. The use cases include models from single cells, neural networks and whole brain models as well as spiking neural networks embedded in simulated agents, all of them addressing different scientific questions.