Lehrstuhl für Allgemeine Zoologie und Neurobiologie

Prof. Dr. Stefan Herlitze - Publikationen

2017 | 2016 | 2015 | 2014 | 2013 | 2011 | 2010 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2001 | 2000 | 1999 | 1998 | 1997 | 1996 | 1990-1994

2017

Kastanenka KV, Herlitze S, Boyden ES, Tsai L, Bacskai BJ (2017)
Optogenetics Shed Light on Alzheimer’s Disease.
EC Neurology ECO.01 (2017): 27-29
PDF-document

Hasegawa E, Maejima T, Yoshida T, Masseck OA, Herlitze S, Yoshioka M, Sakurai T, Mieda M. (2017)
Serotonin neurons in the dorsal raphe mediate the anticataplectic action of orexin neurons by reducing amygdala activity.
Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):E3526-E3535. doi: 10.1073/pnas.1614552114. Epub 2017 Apr 10.
PMID: 28396432
Abstract

Hellinger J, Jägers P, Donner M, Sutt F, Mark MD, Senen B, Tollrian R, Herlitze S. (2017
The Flashlight Fish Anomalops katoptron Uses Bioluminescent Light to Detect Prey in the Dark.
PLoS One. 2017 Feb 8;12(2):e0170489. doi: 10.1371/journal.pone.0170489. eCollection 2017.
PMID: 28178297
Abstract

Mark MD, Schwitalla JC, Groemmke M, Herlitze S. (2017)
Keeping Our Calcium in Balance to Maintain Our Balance.
Biochem Biophys Res Commun. Invited Review. 483: 1040 -1050.

nach oben

2016

Marquitan M, Clausmeyer J, Actis P, Córdoba AL, Korchev Y, Mark MD, Herlitze S and Schuhmann W (2016)
Intracellular Hydrogen Peroxide Detection with Functionalised Nanoelectrodes.
ChemElectroChem. 24 AUG 2016 | DOI: 10.1002/celc.201600390.

Spoida K, Eickelbeck D, Karapinar R, Eckhardt, T, Mark MD, Jancke D, Ehinger BV, König P, Dalkara D, Herlitze S, Masseck OA. (2016)
Melanopsin Variants as Intrinsic Optogenetic On and Off Switches for Transient versus Sustained Activation of G Protein Pathways.
Current Biology 26 (9), 1206–1212

Bomben VC, Aiba I, Qian J, Mark MD, Herlitze S, Noebels JL (2016)
Isolated P/Q Calcium Channel Deletion in Layer VI Corticothalamic Neurons Generates Absence Epilepsy.
J Neurosci. 2016 Jan 13;36(2):405-18. doi: 10.1523/JNEUROSCI.2555-15.2016.
PMID: 26758833
Abstract

nach oben

2015

Mark MD, Krause M, Boele HJ, Kruse W, Pollok S, Kuner T, Dalkara D, Koekkoek S, De Zeeuw CI, Herlitze S. (2015)
Spinocerebellar ataxia type 6 protein aggregates cause deficits in motor learning and cerebellar plasticity.
J Neurosci. Jun 10;35(23):8882-8895. doi: 10.1523/JNEUROSCI.0891-15.2015.
Abstract

Aarse J, Herlitze S, Manahan-Vaughan D (2015)
The requirement of BDNF for hippocampal synaptic plasticity is experience-dependent.
Hippocampus. 2015 Dec 10. doi: 10.1002/hipo.22555. [Epub ahead of print]
PMID: 26662461
Abstract

Lux V, Masseck OA, Herlitze S, Sauvage MM (2015)
Optogenetic Destabilization of the Memory Trace in CA1: Insights into Reconsolidation and Retrieval Processes.
Cereb Cortex. 2015 Nov 29. pii: bhv282. [Epub ahead of print]
PMID: 26620265
Abstract

nach oben

2014

Masseck OA, Mark MD, Herlitze S (2014)
Use of Optogenetic Approaches to Control Intracellular Signaling of G Protein-Coupled Receptors. G-Protein Coupled Receptor Genetics.
Methods in Pharmacology and Toxicology pp. 149-160. Springer Verlag Book Chapter.

Kruse W, Krause M, Aarse J, Mark MD, Manahan-Vaughan D, Herlitze S. (2014)
Optogenetic Modulation and Multi-Electrode Analysis of Cerebellar Networks In Vivo.
DOI: 10.1371/journal.pone.0105589

Spoida K, Masseck OA, Deneris ES, Herlitze S. (2014)
Gq/5-HT2c receptor signals activate a local GABAergic inhibitory feedback circuit to modulate serotonergic firing and anxiety in mice.
Proc. Natl. Acad. Sci. U S A. 111(17):6479-84.
doi: 10.1073/pnas.1321576111

Masseck OA, Spoida K, Dalkara D, Maejima T, Rubelowski JM, Wallhorn L, Deneris ES, Herlitze S (2014)
Vertebrate Cone Opsins Enable Sustained and Highly Sensitive Rapid Control of Gi/o Signaling in Anxiety Circuitry
Neuron, 18 (6):1263-1273
Abstract + Video

nach oben

2013


Maejima T, Wollenweber P, Teusner LUC, Noebels JL, Herlitze S, Mark MD. (2013)
Postnatal loss of P/Q-type channels confined to rhombic-lip-derived neurons alters synaptic transmission at the parallel fiber to Purkinje Cell synapse and replicates genomic Cacna1a mutation phenotype of ataxia and seizures in mice.
The Journal of Neuroscience, doi: 10.1523/JNEUROSCI.5442-12.2013

Maejima T, Masseck OA, Mark MD, Herlitze S (2013)
Modulation of firing and synaptic transmission of serotonergic neurons by intrinsic G protein-coupled receptors and ion channels.
Front Integr Neurosci. 23:7-40, doi: 10.3389/fnint.2013.00040

nach oben

2011


Masseck OA, Rubelowski JM, Spoida K, Herlitze S. (2011)
Light- and drug-activated G-protein-coupled receptors to control intracellular signalling.
Exp Physiol. 2011 Jan;96(1):51-56.

Mark M, Maejima T, Kuckelsberg D, Yoo J, Hyde R, Shah V, Gutierrez D, Moreno R, Kruse W, Noebels J , Herlitze S. (2011)
Delayed postnatal loss of P/Q-type calcium channels recapitulates the absence epilepsy, dyskinesia, and ataxia phenotypes of genomic Cacna1A mutations.
J. Neurosci. 31:4311-4326.

Gutierrez DV, Mark MD, Masseck O, Maejima T, Kuckelsberg D, Hyde RA, Krause M, Kruse W, Herlitze S.(2011)
Optogenetic control of motor coordination by Gi/o protein-coupled vertebrate rhodopsin in cerebellar.
J Biol Chem. 286:25848-25858.

nach oben

2010


Oh E, Maejima T, Liu C, Deneris ES, Herlitze S. (2010)
Substitution of 5HT1A receptor signaling by light-activated G protein coupled receptors.
J. Biol. Chem. 2010 Oct 1;285:30825-30836.

Liu C, Maejima T, Wyler S, Casadeus G, Herlitze S, Deneris ES. (2010)
Pet-1 is required across different stages of life to regulate serotonergic function.
Nature Neuroscience 2010 Oct;13(10):1190-1198.

nach oben

2008


Alilain WJ, Li X, Horn KP, Dhingra R, Dick TE, Herlitze S, Silver J. (2008)
Light-induced rescue of breathing after spinal cord injury.
J Neurosci. 2008 Nov 12;28(46):11862-11870.
Text-document

Rong YP, Aromolaran AS, Bultynck G, Zhong F, Li X, McColl K, Matsuyama S, Herlitze S, Roderick HL, Bootman MD, Mignery GA, Parys JB, De Smedt H, Distelhorst CW. (2008)
Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals.
Mol Cell. 2008 Jul 25;31(2):255-265.

nach oben

2007


Xie M, Li X, Han J, Vogt DL, Wittemann S, Mark MD, Herlitze S. (2007)
Facilitation versus depression in cultured hippocampal neurons determined by targeting of Ca2+ channel Cavbeta4 versus Cavbeta2 subunits to synaptic terminals.
J Cell Biol. 2007 Jul 30;178(3):489-502
Text-document

Armbruster BN, Li X, Pausch MH, Herlitze S, Roth BL. (2007)
Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand.
Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5163-5168. Epub 2007 Mar 2.
Text-document

Herlitze S, Landmesser LT. (2007)
New optical tools for controlling neuronal activity.
Curr Opin Neurobiol. 2007 Feb;17(1):87-94. Epub 2006 Dec 15. Review.

nach oben

2006


Han J, Mark MD, Li X, Xie M, Waka S, Rettig J, Herlitze S. (2006)
RGS2 determines short-term synaptic plasticity in hippocampal neurons by regulating Gi/o-mediated inhibition of presynaptic Ca2+ channels.
Neuron. 2006 Sep 7;51(5):575-586.

nach oben

2005


Li X, Gutierrez DV, Hanson MG, Han J, Mark MD, Chiel H, Hegemann P, Landmesser LT, Herlitze S. (2005)
Fast noninvasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin.
Proc Natl Acad Sci U S A. 2005 Dec 6; 102(49):17816-17821.
Text-document

Scott MM, Wylie CJ, Lerch JK, Murphy R, Lobur K, Herlitze S, Jiang W, Conlon RA, Strowbridge BW, Deneris ES. (2005)
A genetic approach to access serotonin neurons for in vivo and in vitro studies.
Proc Natl Acad Sci U S A. 2005 Nov 8; 102(45):16472-16477.
Text-document

Li X, Hümmer A, Han J, Xie M, Melnik-Martinez K, Moreno RL, Buck M, Mark MD, Herlitze S. (2005)
G protein beta2 subunit-derived peptides for inhibition and induction of G protein pathways. Examination of voltage-gated Ca2+ and G protein inwardly rectifying K+ channels.
J Biol Chem. 2005 Jun 24; 280(25):23945-23959.


Herlitze S, Mark, MD. (2005)
Distribution and targeting of Ca2+ channels. Book Title:Voltage-gated Calcium Channels,
Editor: Gerald Zamponi, Chapter 7, 113-140, Kluwer Academic Plenum Publ., ISBN: 0-306-47840-4.

nach oben

2004


Kurata HT, Phillips LR, Rose T, Loussouarn G, Herlitze S, Fritzenschaft H, Enkvetchakul D, Nichols CG, Baukrowitz T. (2004)
Molecular basis of inward rectification: polyamine interaction sites located by combined channel and ligand mutagenesis.
J Gen Physiol. 2004 Nov; 124(5):541-554.
Text-document

nach oben

2003


Herlitze S, Xie M, Han J, Hummer A, Melnik-Martinez KV, Moreno RL, Mark MD. (2003)
Targeting mechanisms of high voltage-activated Ca2+ channels.
J Bioenerg Biomembr. 2003 Dec; 35(6):621-637.


Hümmer A, Delzeith O, Gomez SR, Moreno RL, Mark MD, Herlitze S. (2003)
Competitive and synergistic interactions of G protein beta(2) and Ca(2+) channel beta(1b) subunits with Ca(v)2.1 channels, revealed by mammalian two-hybrid and fluorescence resonance energy transfer measurements.
J Biol Chem. 2003 Dec 5; 278(49):49386-49400.

nach oben

2001


Herlitze S, Zhong H, Scheuer T, Catterall WA. (2001)
Allosteric modulation of Ca2+ channels by G proteins, voltage-dependent facilitation, protein kinase C, and Ca(v)beta subunits.
Proc Natl Acad Sci U S A. 2001 Apr 10; 98(8):4699-4704.
Text-document

nach oben

2000


Mark MD, Wittemann S, Herlitze S. (2000)
G protein modulation of recombinant P/Q-type calcium channels by regulators of G protein signalling proteins.
J Physiol. 2000 Oct 1; 528 Pt 1:65-77.
Text-document

Mark MD, Herlitze S. (2000)
G-protein mediated gating of inward-rectifier K+ channels.
Eur J Biochem. 2000 Oct; 267(19):5830-5836.


Mark MD, Ruppersberg JP, Herlitze S. (2000)
Regulation of GIRK channel deactivation by Galpha(q) and Galpha(i/o) pathways.
Neuropharmacology. 2000 Sep; 39(12):2360-2373.


Wittemann S, Mark MD, Rettig J, Herlitze S. (2000)
Synaptic localization and presynaptic function of calcium channel beta 4-subunits in cultured hippocampal neurons.
J Biol Chem. 2000 Dec 1; 275(48):37807-37814.

nach oben

1999


Herlitze S, Ruppersberg JP, Mark MD. (1999)
New roles for RGS2, 5 and 8 on the ratio-dependent modulation of recombinant GIRK channels expressed in Xenopus oocytes.
J Physiol. 1999 Jun 1; 517 ( Pt 2):341-352.
Text-document

nach oben

1998


Baukrowitz T, Schulte U, Oliver D, Herlitze S, Krauter T, Tucker SJ, Ruppersberg JP, Fakler B. (1998)
PIP2 and PIP as determinants for ATP inhibition of KATP channels.
Science. 1998 Nov 6; 282(5391):1141-1144.

nach oben

1997


Herlitze S, Hockerman GH, Scheuer T, Catterall WA. (1997)
Molecular determinants of inactivation and G protein modulation in the intracellular loop connecting domains I and II of the calcium channel alpha1A subunit.
Proc Natl Acad Sci U S A. 1997 Feb 18; 94(4):1512-1516.
Text-document

nach oben

1996


Herlitze S, Garcia DE, Mackie K, Hille B, Scheuer T, Catterall WA. (1996)
Modulation of Ca2+ channels by G-protein beta gamma subunits.
Nature. 1996 Mar 21; 380(6571):258-262


Herlitze S, Villarroel A, Witzemann V, Koenen M, Sakmann B. (1996)
Structural determinants of channel conductance in fetal and adult rat muscle acetylcholine receptors.
J Physiol. 1996 May 1;492 ( Pt 3):775-787.
Text-document

nach oben

1994


Fakler B, Herlitze S, Amthor B, Zenner HP, Ruppersberg JP. (1994)
Short antisense oligonucleotide-mediated inhibition is strongly dependent on oligo length and concentration but almost independent of location of the target sequence.
J Biol Chem. 1994 Jun 10;269(23):16187-16194.

nach oben

1993


Herlitze S, Raditsch M, Ruppersberg JP, Jahn W, Monyer H, Schoepfer R, Witzemann V. (1993)
Argiotoxin detects molecular differences in AMPA receptor channels.
Neuron. 1993 Jun;10(6):1131-1140.

nach oben

1992


Villarroel A, Herlitze S, Witzemann V, Koenen M, Sakmann B. (1992)
Asymmetry of the rat acetylcholine receptor subunits in the narrow region of the pore.
Proc Biol Sci. 1992 Sep 22;249(1326):317-324.

nach oben

1991


Villarroel A, Herlitze S, Koenen M, Sakmann B. (1991)
Location of a threonine residue in the alpha-subunit M2 transmembrane segment that determines the ion flow through the acetylcholine receptor channel.
Proc Biol Sci. 1991 Jan 22;243(1306):69-74.

nach oben

1990


Herlitze S, Koenen M. (1990)
A general and rapid mutagenesis method using polymerase chain reaction.
Gene. 1990 Jul 2;91(1):143-147.