Department of General Zoology and Neurobiology
Faculty Biology and Biotechnology » Prof. Dr. Stefan Herlitze

Movie to publication:
Vertebrate Cone Opsins Enable Sustained and Highly Sensitive Rapid Control of Gi/o Signaling in Anxiety Circuitry. Anxiety Circuitry. Neuron, 18 (6):1263-1273

Video to:Vertebrate Cone Opsins Enable Sustained and Highly Sensitive Rapid Control of Gi/o Signaling in Anxiety Circuitry. Anxiety Circuitry. Neuron, 18 (6):1263-1273

Insights into the Research Department of Neuroscience
Movie at the IBRO-World Congress

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Investigating the origins of spinocerebellar ataxia 6
Scientists at the Ruhr-Universität Bochum established a mouse model for the human disease SCA6. SCA6 is characterized by movement deficits and caused by similar genetic alterations as Chorea Huntington. The mouse model will be used to investigate the disease mechanisms. Experiments suggest that an impairment of eye blink conditioning could be an early disease symptom. The team from the Department of Zoology and Neurobiology published their data in “The Journal of Neuroscience”; the work was highlighted by the editor’s commentary. (mehr)


Mark MD, Schwitalla JC, Groemmke M, Herlitze S. (2016)
Keeping Our Calcium in Balance to Maintain Our Balance.
Biochem Biophys Res Commun. pii: S0006-291X(16)31135-4.
doi: 10.1016/j.bbrc.2016.07.020.
[Epub ahead of print]

Spoida K, Eickelbeck D, Karapinar R, Eckhardt, T, Mark MD, Jancke D, Ehinger BV, König P, Dalkara D, Herlitze S, Masseck OA. (2016)
Melanopsin Variants as Intrinsic Optogenetic On and Off Switches for Transient versus Sustained Activation of G Protein Pathways.
Current Biology 26 (9), 1206–1212

A.Thiele, C. Brandt, M. Dasliva, S. Gotthardt, D. Chicharro, S. Panzeri and C. Distler
Attention Induced Gain Stabilization in Broad and Narrow-Spike Cells in the Frontal Eye-Field of Macaque Monkeys.
The Journal of Neuroscience, 36(29):7601–7612 (2016)

Bomben VC, Aiba I, Qian J, Mark MD, Herlitze S, Noebels JL (2016)
Isolated P/Q Calcium Channel Deletion in Layer VI Corticothalamic Neurons Generates Absence Epilepsy.
J Neurosci. 2016 Jan 13;36(2):405-18. doi: 10.1523/JNEUROSCI.2555-15.2016.
PMID: 26758833


Aarse J, Herlitze S,
Manahan-Vaughan D (2015)

The requirement of BDNF for hippocampal synaptic plasticity is experience-dependent.
Hippocampus. 2015 Dec 10.
doi: 10.1002/hipo.22555.
[Epub ahead of print]
PMID: 26662461

Lux V, Masseck OA, Herlitze S, Sauvage MM (2015)
Optogenetic Destabilization of the Memory Trace in CA1: Insights into Reconsolidation and Retrieval Processes.
Cereb Cortex. 2015 Nov 29.
pii: bhv282. [Epub ahead of print]
PMID: 26620265

Mark MD, Krause M, Boele HJ, Kruse W, Pollok S, Kuner T, Dalkara D, Koekkoek S, De Zeeuw CI, Herlitze S.
Spinocerebellar ataxia type 6 protein aggregates cause deficits in motor learning and cerebellar plasticity.
J Neurosci. Jun 10;35(23):8882-8895. doi:10.1523/JNEUROSCI.0891-15.2015.

M. Sanayei, J. L. Herrero, C. Distler & A. Thiele
Attention and normalization circuits in macaque V1.
European J. Neuroscience doi:10.1111/ejn.12857