RUB »AG Angewandte Mikrobiologie » Publikationen


  1. U. Siemeling, L. Wallbaum, D. Weismann, D. Löber, C. Bruhn, P. Prochnow, J. E. Bandow. Stable and persistent acyclic diaminocarbenes with cycloalkyl substituents and their transformation to b-lactams by uncatalysed carbonylation with CO. Chemistry doi: 10.1002/chem.201805307
  2. J. Borgmann, S. Schäkermann, J. E. Bandow, F. Narberhaus. 2018. A small regulatory RNA controls cell wall biosynthesis and antibiotic resistance in the plant pathogen Agrobacterium tumefaciens. mBio 9:e02100-18
  3. W. Streciwilk, A. Terenzi, F. Lo Nardo, P. Prochnow, J. E. Bandow, B. K. Keppler, I. Ott. 2018. Synthesis and biological evaluation of organometallic complexes bearing bis-1,8-naphthalimide ligands. European Journal of Inorganic Chemistry Issue 26:3104-12
  4. W. Streciwilk, A. Terenzi, X. Cheng, L. Hager, Y. Dabiri, P. Prochnow, J. E. Bandow, S. Wölfl, B. Keppler, I. Ott. 2018. Fluorescent organometallic rhodium(I) and ruthenium(II) metallodrugs with 4-ethylthio-1,8-naphthalimide ligands: antiproliferative effects, cellular uptake and DNA-interaction.  European Journal of Medicinal Chemistry 156:148-61
  5. J. Benedikt, M. M. Hefny, A. Shaw, B. Buckley, F. Iza, S. Schäkermann, J. E. Bandow. 2018. The fate of plasma-generated oxygen atoms in aqueous solutions: non-equilibrium atmospheric plasmas as an efficient source of O(aq). Physical Chemistry Chemical Physics 20:12037-42
  6. C. H. R. Senges, A. Al-Dilaimi, D. H. Marchbank, D. Wibberg, A. Winkler, B. Haltli, M. Nowrousian, J. Kalinowski, R. G. Kerr, J. E. Bandow. 2018. The secreted metabolome of Streptomyces chartreusis and implications for bacterial chemistry.Proceedings of the National Academy of Sciences USA 115:2490-5
  7. J. Saising, M.-T. Nguyen, T. Härtner, P. Ebner, A. Al Mamun Bhuyan, A. Berscheid, M. Muehlenkamp, S. Schäkermann, N. Kumari, M. Maier, S. P. Voravuthikunchai, J. Bandow, F. Lang, H. Brötz-Oesterhelt, F. Goetz. 2018. Rhodomyrtone (Rom) is a membrane-active compound.BBA – Biomembranes 1114-24
  8. D. Siegmund, N. Lorenz, Y. Gothe, C. Spies, B. Geissler, P. Prochnow, P. Nürnberger, J. E. Bandow, N. Metzler-Nolte. 2017. Benzannulated Re(I)-NHC complexes: Synthesis, photophysical properties and antimicrobial activity. Dalton Transactions 46:15269-79 
  9. P. Sukul, S. Schäkermann, J. E. Bandow, A. Kusnezowa, M. Nowrousian, L. I. Leichert. 2017. Simple discovery of bacterial biocatalysts from environmental samples through functional metaproteomics. Microbiome 5:28
  10. K. Scheinpflug, M. Wenzel, O. Krylova, J. E. Bandow, M. Dathe, H. Strahl. 2017. Antimicrobial peptide cWFW kills by combining lipid phase separation with autolysis. Scientific Reports7:44332
  11. J.-W. Lackmann, M. Fiebrandt, M. Raguse, K. Kartaschew, M. Havenith, J. E. Bandow, R. Moeller, P. Awakowicz, K. Stapelmann. 2017. An intercomparison study of different biological systems to low-pressure hydrogen peroxide evaporation combined with hydrogen plasma treatment. Plasma Polymers and Processes DOI: 10.1002/ppap.201600199
  12. S. Schäkermann, P. Prochnow, J. E. Bandow. 2017. Label-free quantitation of ribosomal proteins from Bacillus subtilis for antibiotic research. Methods in Molecular Biology 1520:291-306
  13. J. C. Slootweg, P. Prochnow, S. Bobersky, J. E. Bandow, N. Metzler-Nolte. 2017. Exploring structure-activity relationship in synthetic antimicrobial peptides (synAMPs) by ferrocene scan. European Journal of Inorganic Chemistry 2017:360-7
  14. A. Müller, M. Wenzel, H. Strahl, F. Grein, T. N. V. Saaki, B. Kohl, T. Siersma, J. E. Bandow, H.-G. Sahl, T. Schneider, L. W. Hamoen. 2016. Daptomycin inhibits cell envelope synthesis by interfering with fluid membrane microdomains. Proceedings of the National Academy of Sciences USA 113:E7077-86
  15. M. Wenzel, P. Prochnow, C. Mowbray, C. Vuong, S. Höxtermann, J. J. Stepanek, H. B. Albada, J. Hall, N. Metzler-Nolte, J. E. Bandow*. 2016. Towards profiles of resistance development and toxicity for the small cationic hexapeptide RWRWRW-NH2. Frontiers in Cell and Developmental Biology 4:86 doi: 10.3389/fcell.2016.00086
  16. J. J. Stepanek, S. Schäkermann, M. Wenzel, P. Prochnow, J. E. Bandow*. 2016. Purine biosynthesis is the bottleneck in trimethoprim-treated B. subtilis. Proteomics - Clinical Applications 10:1036-48
  17. A. Müller, J. Eller, F. Albrecht, P. Prochnow, K. Kuhlmann, J. E. Bandow, A. J. Slusarenko, L. I. O. Leichert. 2016. Allicin induces thiol stress in bacteria through S-allylmercapto modification of protein cysteines. Journal of Biological Chemistry 291:11477-90
  18. J. J. Stepanek, T. Lukežič, I. Teichert, H. Petković, J. E. Bandow*. 2016. Dual mechanism of action of the atypical tetracycline chelocardin. BBA Proteins and Proteomics 1864:645-54
  19. B. C. Hoffknecht, P. Prochnow, J. E. Bandow, N. Metzler-Nolte. 2016. Influence of metallocene substitution on the antibacterial activity of multivalent peptide conjugates. Journal of Inorganic Biochemistry 160:246-9
  20. M.-C. Hoffmann, E. Wagner, S. Langklotz, Y. Pfänder, S. Hött, J. E. Bandow, B. Masepohl. Proteome profiling of Rhodobacter capsulatus molybdenum response reveals a role of NIFIscA in nitrogen fixation by Fe-nitrogenase. Journal of Bacteriology 198:633-43
  21. M. Wenzel, P. Schriek, P. Prochnow, H. B. Albada, N. M. Metzler-Nolte, J. E. Bandow*. Influence of lipidation on the mode of action of a small RW-rich antimicrobial peptide. BBA Biomembranes 1858:1004-11
  22. J.-W. Lackmann, S. Baldus, E. Steinborn, E. Edengeiser, F. Kogelheide, S. Langklotz, S. Schneider, L. I. O. Leichert, J. Benedikt, P. Awakowicz, J. E. Bandow*. A dielectric barrier discharge terminally inactivates RNase A by oxidizing sulfur-containing amino acids and breaking structural disulfide bonds. Journal of Physics D: Applied Physics 48:494003
  23. S. Schneider, F. Jarzina, J.-W. Lackmann, J. Golda, V. Schulz-von der Gathen, J. E. Bandow, J. Benedikt. 2015. Summarizing results on the performance of a selective set of atmospheric plasma jets for separation of photons and reactive particles. Journal of Physics D: Applied Physics 48:444001
  24. B. C. Hoffknecht, D. Worms, P. Prochnow, J. E. Bandow, N. Metzler-Nolte. 2015. Influence of multivalency of ultrashort Arg-Trp-based antimicrobial peptides (AMP) on the antibacterial activity. ChemMedChem 10:1564-9
  25. M. Strack, S. Langklotz, J. E. Bandow, N. Metzler-Nolte, H. B. Albada. 2015. Synthesis of bisarylethyne-peptide conjugates. Organic Chemistry Frontiers 2:531-5
  26. M. Wenzel, C. H. R. Senges, J. Zhang, S. Suleman, M. Nguyen, P. Kumar, A. I. Chiriac, J. J. Stepanek, N. Raatschen, C. May, U. Krämer, H.-G. Sahl, S. K. Straus*, J. E. Bandow*. 2015. Antimicrobial peptides from the aurein family form ion-selective pores in Bacillus subtilis. ChemBioChem 16:1101-8
  27. E. Edengeiser, J.-W. Lackmann, E. Bründermann, S. Schneider, J. Benedikt, J. E. Bandow*, M. Havenith. 2015. Synergistic effects of atmospheric pressure plasma-emitted components on DNA oligomers: A Raman spectroscopic study. Journal of Biophotonics 8:918-24
  28. B. C. Hoffknecht, H. B. Albada, M. Sturm, P. Prochnow, J. E. Bandow, N. Metzler-Nolte. 2015. Synthesis and antibacterial activity of trivalent ultrashort Arg-Trp-based antimicrobial peptides (AMPs). Medicinal Chemistry Communications 6:372-6
  29. M. Patra, M. Wenzel, P. Prochnow, V. Pierroz, G. Gasser, J. E. Bandow, N. Metzler-Nolte. 2015. An organometallic structure-activity relationship study reveals the essential role of a Re(CO)3 moiety in the activity against gram-positive pathogens including MRSA. Chemical Science 6:214-24
  30. A. Müller, N. Lupilova, K. Kuhlmann, S. Langklotz, J. E. Bandow, L. I. O. Leichert. 2014. Activation of RidA chaperone function by N-chlorination. Nature Communications 5:5804
  31. S. Langklotz, J. E. Bandow*. 2014. Antibakterielle Strategien und bakterielle Abwehrmechanismen. BIOspektrum 20:744-6
  32. H. B. Albada, P. Prochnow, S. Bobersky, J. E. Bandow, N. Metzler-Nolte. 2014. Highly active antibacterial ferrocenoylated or ruthenocenoylated Arg-Trp peptides can be discovered by an L-to-D substitution scan. Chemical Science 5:4453-9
  33. K. E. Overkamp, S. Langklotz, M. Aras, S. Helling, K. Marcus, J. E. Bandow, K. Hoef-Emden, N. Frankenberg-Dinkel. 2014. Chromophore composition of the phycobiliprotein Cr-PC577 from the cryptophyte Hemiselmis pacifica. Photosynthesis Research DOI: 10.1007/s11120-014-0029-1
  34. J.-W. Lackmann, J. E. Bandow*. 2014. Inactivation of microbes and macromolecules by atmospheric-pressure plasma jets. Applied Microbiology and Biotechnology 98:6205-13
  35. D. Münch, A. Müller, T. Schneider, B. Kohl, M. Wenzel, J. E. Bandow, S. Maffioli, M. Sosio, S. Donadio, R. Wimmer, H.-G. Sahl. 2014. The lantibiotic NAI-107 binds to bactoprenol-bound cell wall precursors and impairs membrane functions. Journal of Biological Chemistry289:12063-76
  36. M. Wenzel, A. I. Chiriac, A. Otto, D. Zweytick, C. May, C. Schumacher, R. Gust, H. B. Albada, M. Penkova, U. Krämer, R. Erdmann, N. Metzler-Nolte, S. K. Straus, E. Bremer, D. Becher, H. Brötz-Oesterhelt, H.-G. Sahl, J. E. Bandow*. 2014. Small cationic antimicrobial peptides delocalize peripheral membrane proteins. Proceedings of the National Academy of Sciences USA 111:E1409-18
  37. T. Schulz, C. Färber, M. Leibold, C. Bruhn, P. Prochnow, J. E. Bandow, T. Schneider, T. Porsch, M. C. Holthausen, U. Siemeling. 2014. Diastereoselective synthesis of a bicyclic β-lactam with penicillin G-like spectrum of activity by carbonylation of an acyclic diaminocarbene. Chemical Communications 50:2341-3
  38. K. Stapelmann, J.-W. Lackmann, I. Bürger, J. E. Bandow*, P. Awakowicz*. 2014. An H2 very high frequency capacitively coupled plasma inactivates glyceraldehyde 3-phosphate dehydrogenase (GapDH) more efficiently than UV photons and heat combined. Journal of Physics D: Applied Physics 47:085402
  39. J.-W. Lackmann, E. Edengeiser, S. Schneider, J. Benedikt, M. Havenith, J. E. Bandow*. 2013. Effects of the effluent of a microscale atmospheric pressure plasma jet operated with He/O2 gas on bovine serum albumin. Plasma Medicine 3:115-24 (DOI: 10.1615/PlasmaMed.2014008858)
  40. H. B. Albada, P. Prochnow, S. Bobersky, S. Langklotz, J. E. Bandow, N. Metzler-Nolte. 2013. Short antibacterial peptides with significantly reduced hemolytic activity can be identified by a systematic L-to-D exchange scan of their amino acid residues. ACS Combinatorial Science 15:585-92
  41. J.-W. Lackmann, S. Schneider, E. Edengeiser, F. Jarzina, S. Brinckmann, E. Steinborn, M. Havenith, J. Benedikt, J. E. Bandow*. 2013. Photons and particles from atmospheric-pressure plasma inactivate bacteria and biomolecules independently and synergistically. Journal of the Royal Society Interface 10: 20130591
  42. A. Cimdins, J. Roßmanith, S. Langklotz, J. E. Bandow, F. Narberhaus. 2013. Differential control of Salmonella heat shock operons by structured mRNAs. Molecular Microbiology 89:715-31
  43. M. Wenzel, M. Patra, C. H. R. Senges, I. Ott, J. J. Stepanek, A. Pinto, P. Prochnow, C. Vuong, S. Langklotz, N. Metzler-Nolte*, J. E. Bandow*. 2013. Target identification of potent antibacterial hetero-tri-organometallic compounds – a structurally new class of antibiotics. ACS Chemical Biology 8:1442-50
  44. N. Raatschen, M. Wenzel, L. I. O. Leichert, P. Düchting, U. Krämer, J. E. Bandow*. 2013. Extracting iron and manganese from bacteria with ionophores – a mechanism against competitors characterized by increased potency in environments low in micronutrients. Proteomics 13:1358-70
  45. M. Strack, S. Langklotz, J. E. Bandow, N. Metzler-Nolte, H. B. Albada. 2012. A silyl-based alkyne modifying (SAM)-linker for the preparation of C-terminal acetylene-derivatized protected peptides. Journal of Organic Chemistry 77:9954-8
  46. H. B. Albada, A.-I. Chiriac, M. Wenzel, M. Penkova, J. E. Bandow, H.-G. Sahl, N. Metzler-Nolte. 2012. Modulating the activity of short arginine-tryptophan containing antibacterial peptides with N-terminal metallocenyl groups. Beilstein Journal of Organic Chemistry 8:1753-64
  47. H. B. Albada, P. Prochnow, S. Bobersky, S. Langklotz, P. Schriek, J. E. Bandow, N. Metzler-Nolte. 2012. Tuning the activity of a short Arg-Trp antimicrobial peptide by lipidation of a C- or N-terminal lysine side-chain. ACS Medicinal Chemistry Letters 3:980-84
  48. M. Wenzel, B. Kohl, D. Münch, N. Raatschen, H. B. Albada, L. Hamoen, N. Metzler-Nolte, H.-G. Sahl, J. E. Bandow*. 2012. Proteomic response of Bacillus subtilis to lantibiotics reflects differences in interaction with the cytoplasmic membrane. Antimicrobial Agents and Chemotherapy 56:5749-57
  49. N. Raatschen, J. E. Bandow*. 2012. 2D gel-based proteomic approaches to antibiotic drug discovery in Current Protocols in Microbiology (John Wiley & Sons, Inc. edited by Richard Coico, Timothy Kowalik, John Quarles, Brian Stevenson, and Ronald Taylor) 1F.2.1-1F.2.16
  50. M. Patra, G. Gasser, M. Wenzel, K. Merz, J. E. Bandow, N. Metzler-Nolte. 2012. Sandwich and half-sandwich derivatives of platensimycin: synthesis and biological evaluation. Organometallics 31:5760-71
  51. S. Schneider, J.-W. Lackmann, D. Ellerweg, B. Denis, F. Narberhaus, J. Bandow, J. Benedikt. 2012. The role of VUV radiation in the inactivation of bacteria with an atmospheric pressure plasma jet. Plasma Processes and Polymers 9:561-568
  52. J.-W. Lackmann, S. Schneider, F. Narberhaus, J. Benedikt, J. E. Bandow*. 2012. Characterization of damage to bacteria and bio-macromolecules caused by (V)UV radiation and particles generated by a microscale atmospheric pressure plasma jet. In Plasma in bio-decontamination, medicine and food security, NATO Science for Peace and Security Series A: Chemistry and Biology (Springer) 17-29
  53. S. Schneider, J.-W. Lackmann, F. Narberhaus, J. Bandow, J. Benedikt. 2011. Separation of VUV/UV photons and reactive particles in the effluent of a He/O2 atmospheric pressure plasma jet. Journal of Physics D: Applied Physics 44:295201-10
  54. M. Patra, G. Gasser, M. Wenzel, K. Merz, J. E. Bandow, N. Metzler-Nolte. 2011. Synthesis of optically active ferrocene-containing platensimycin derivatives with a C6-C7 substitution pattern. European Journal of Inorganic Chemistry 22:3295-302
  55. M. Wenzel, J. E. Bandow*. 2011. Proteomic signatures in antibiotic research. Proteomics 11:3256-68
  56. M. Wenzel, M. Patra, D. Albrecht, D. Y.-K. Chen, K. C. Nicolaou, N. Metzler-Nolte, J. E. Bandow*. 2011. Proteomic signature of fatty acid biosynthesis inhibition available for in vivo mechanism of action studies. Antimicrobial Agents and Chemotherapy 55:2590-2596
  57. G. Y. C. Leung, H. Li, Q.-Y. Toh, A. M.-Y. Ng, R. J. Sum, J. E. Bandow, D. Y.-K. Chen. 2011. Total synthesis and biological evaluation of Fab-inhibitory antibiotic platencin and analogues thereof. European Journal of Organic Chemistry 2011:183-96
  58. M. Patra, G. Gasser, M. Wenzel, K. Merz, J. E. Bandow, N. Metzler-Nolte. 2010. Synthesis and biological evaluation of ferrocene-containing bioorganometallics inspired by the antibiotic platensimycin lead structure. Organometallics 29:4312-4319
  59. B. Fränzel, C. Frese, M. Penkova, N. Metzler-Nolte, J. E. Bandow, D. A. Wolters. 2010. Corynebacterium glutamicum exhibits a membrane related response to a small ferrocene-conjugated antimicrobial peptide. Journal of Biological Inorganic Chemistry 15:1293-303
  60. S. Klüsener, S. Hacker, Y.-L. Tsai, J. Bandow, R. Gust, E.-M. Lai, F. Narberhaus. 2010. Proteomic and transcriptomic characterization of a virulence-deficient phosphatidylcholine-negative Agrobacterium tumefaciens mutant. Molecular Genetics and Genomics 283:575-89
  61. J. E. Bandow*. 2010. Comparison of protein enrichment strategies for proteome analysis of plasma. Proteomics 10:1416-25
  62. J. E. Bandow, N. Metzler-Nolte. 2009. New ways of killing the beast: prospects for inorganic-organic hybrid nanomaterials as anti-bacterial agents. ChemBioChem 10:2847-50
  63. M. Patra, G. Gasser, A. Pinto, K. Merz, I. Ott, J. E. Bandow, N. Metzler-Nolte. 2009. Synthesis and biological evaluation of chromium bioorganometallics based on the antibiotic platensimycin lead structure. ChemMedChem 4:1930-8
  64. J. E. Bandow*, J. D. Baker, M. Berth, C. Painter, O. J. Sepulveda, I. Kilty, R. A. Vanbogelen. 2008. Improved image analysis workflow for 2D gels enables large-scale 2D gel-based proteomics studies – COPD biomarker discovery study. Proteomics 8:3030-41
  65. X. Song, J. Bandow, J. Sherman, J. D. Baker, P. W. Brown, M. T. McDowell, M. Molloy. 2008. iTRAQ experimental design for plasma biomarker discovery. Journal of Proteome Research 7:2952-8
  66. F. Goodsaid, J. E. Bandow, H. Mischak. 2007. Grand Rounds in Proteomics at the FDA. Proteomics Clinical Applications 1:1526-31
  67. J. E. Bandow*, M. Hecker. 2007. Proteomic profiling of cellular stresses in Bacillus subtilis reveals cellular networks and assists in elucidating antibiotic mechanism of action in Applications of Functional Genomics and Systems Biology to the Development of Anti-infectives (edited by Helena I.M. Boshoff and Clifton E. Barry 3rd in Progress in Drug Research (Birkhaeuser Verlag Publishing edited by Alex Matter and Paul Herrling). 64:81-101
  68. J. E. Bandow*. 2005. Overview of proteomics approaches to antibiotic drug discovery in Current Protocols in Microbiology (John Wiley & Sons, Inc. edited by Richard Coico, Timothy Kowalik, John Quarles, Brian Stevenson, and Ronald Taylor) Unit 1F.2.1-1F.2.17
  69. H. Brötz-Oesterhelt, D. Beyer, H.-P. Kroll, W. Schroeder, B. Hinzen, S. Raddatz, H. Paulsen, J. E. Bandow, H.-G. Sahl, H. Labischinski. 2005. Dysregulation of bacterial proteolytic machinery by a new class of antibiotics. Nature Medicine 11:1082-1087
  70. H. Brötz-Oesterhelt, J. E. Bandow, H. Labischinski. 2004. Bacterial proteomics and its role in antibacterial drug discovery. Mass Spectrometry Reviews 24: 549-565
  71. U. Sender, J. E. Bandow, S. Engelmann, U. Lindequist, M. Hecker. 2004. Proteomic signatures for daunomycin and adriamycin in Bacillus subtilis. Pharmazie 59:65-70
  72. M. Hecker, J. E. Bandow, J. Bernhardt, H. Labischinski, H. Brötz-Oesterhelt. 2003. Physiologische Proteomanalyse – von Proteomsignaturen zu Wirkmechanismen von Antibiotika. BIOspektrum. Sonderausgabe 9:453-455
  73. J. E. Bandow, H. Brötz, L. I. O. Leichert, H. Labischinski, M. Hecker. 2003. Proteomic approach to understanding antibiotic action. Antimicrobial Agents and Chemotherapy 47:948-955
  74. J. E. Bandow*, D. Becher, K. Büttner, F. Hochgräfe, C. Freiberg, H. Brötz, M. Hecker. 2003. The role of peptide deformylase in protein biosynthesis – a proteomic study. Proteomics 3:299-306
  75. T. Kaan, G. Homuth, U. Mäder, J. E. Bandow, T. Schweder. 2002. Genome-wide transcriptional profiling of the Bacillus subtilis cold-shock response. Microbiology 148:3441-3455
  76. J. E. Bandow, H. Brötz, M. Hecker. 2002. Bacillus subtilis tolerance of moderate concentrations of rifampin involves the sB-dependent general and multiple stress response. Journal of Bacteriology 184:459-467