The research area "Medical Bioinformatics" is headed by PD Dr. Martin Eisenacher and acts as a link between applied Proteomics of the other research areas of the Medical Proteome Center and methodical bioinformatics/biostatistics.
Besides infrastructural responsibilities for the MPC (such as the server virtualization system with numerous evaluation servers and databases, the high performance compute cluster as well as the archive and backup solutions), the department consists of the two research groups "Algorithmic Proteomics" and "Computational Quantitative Proteomics". They conduct their own research and develop new methods, algorithms, evaluation workflows and software solutions for the statistically valid evaluation of proteomics data. The division is also involved in the development of standard data formats for the annotation of (meta-)data and for the storage of proteomics spectra and results according to FAIR principles.
Since 2014, the research area "Medical Bioinformatics" has been involved in the BMBF-funded "German Network for Bioinformatics Infrastructure (de.NBI)", in which our expertise is offered in various tool- or evaluation-based services (see here). As German node, de.NBI is part of the European ELIXIR infrastructure (https://elixir-europe.org/). De.NBI operates its own cloud infrastructure, in which some of our services can be executed cross-platform and computationally efficient.
In the research building "PRODI - molecular protein diagnostics" we evaluate data from different clinical and instrumental columns across platforms. This is intended to identify and validate early biomarkers for neurodegenerative diseases such as Alzheimer's and Parkinson's disease and for
cancers such as colon and lung cancer. We offer courses in bioinformatics in different faculties and study courses, and we regularly allocate projects for internships, bachelor, master and doctoral theses.
PD Dr. Martin Eisenacher
ProDi, Raum E2.269
Tel.: +49 234 32-18104
Fax: +49 234 32-14496