Microbes dominate our planet. This enormous success is reflected in the versatility in primary and secondary metabolism that allows the acclimation of microorganisms to various ecological niches. Many of the responsible enzymes and pathways are not only of fundamental interest for basic research, but also attractive for biotechnological and medical applications.
The proposed Research Training Group “Microbial substrate conversion (MiCon)” aims at understanding the mechanistic principles of microbial metabolic processes at the molecular level. The enzymes and pathways under investigation are involved in the synthesis of small molecules like hydrogen, the biosynthesis, modification and degradation of lipids, and the production of secondary metabolites.
The participating researchers contribute a broad spectrum of microbiological, molecular biological, biochemical and biophysical techniques whose combination will gain comprehensive insights into the studied processes. A well-established network of internationally recognized principal investigators from various disciplines guarantees the success of the scientific programme. A comprehensive and structured qualification programme based on two local graduate schools is complemented by specific modules tailored to the interests of doctoral researchers in MiCon. It includes an internship in an academic or industrial group outside Bochum, and guaranties that early career researchers graduating from the RTG can build on a solid, yet individual education providing excellent qualifications to prevail in the competitive job market.