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Mass Spectrometry is an analytical method to determine the exact mass and the quantitative occurrence of a charged compound.
The following questions might be tackled by mass spectrometry

- elemental composition, molecular formula
- structure determination by fragmentation
- quantitative composition of complex mixtures (GC-MS, LC-MS)
- Proteomics, Protein analytics
VG Instruments Autospec / EBEE-Geometry

Electron impact (EI)
Analytics of samples with an evaporation point of max. 300°C; mass range: m/z 30-800 amu
EI-spectra yield mostly fragment ions.
Molecular ions are not always observed.
High resolution feature with ca 6000-8000 resolution


Analytics of polar compounds, which can be resolved in standard FAB-matrices (NBA, lactic acid, glycerine)
FAB-spectra show a significant number of matrix peaks, (pseudo) molecular ions, fragment ions and adducts.
mass range: m/z 30-2200 amu
Finnigan GCQ Iontrap


GC-MS with autosampler

Electron impact

(EI) (+/-)
Chemical Ionization (CI)

Mass range: m/z 10-1000 amu


Jeol AccuTOF GCv  
EI-mass spectra are possible for larger molecules; accurate mass measurement to determine the elemental composition.
Ionization techniques: EI, FD(LIFDI) Mass range: m/z 30-3200
Resolving power: R = 6000 FWHM (Full Width at Half Maximum)
Liquid Injection Field Desorption Ionization (
enables the measurement of air-sensitve organometallic compounds
0,2-1ng/ml samples in toluene or methanol( not water or acetonitrile) in screw cap flasks with septum.

Investigation forms and instructions as a PDF ducument