Publications

2017

  • Jansen S, Gottschling C, Faissner A, Manahan-Vaughan D(2017). Intrinsic cellular and molecular properties of in vivo hippocampal synaptic plasticity are altered in the absence of key synaptic matrix molecules. Hippocampus. 2017 Aug;27(8):920-933. doi: 10.1002/hipo.22742. Epub 2017 May 29.
  • Lugo-Hernandez E, Squire A, Hagemann N, Brenzel A, Sardari M, Schlechter J, Sanchez-Mendoza EH, Gunzer M, Faissner A, Hermann DM (2017). 3D visualization and quantification of microvessels in the whole ischemic mouse brain using solvent-based clearing and light sheet microscopy. J Cereb Blood Flow Metab. 2017 Jan 1:271678X17698970. doi: 10.1177/0271678X17698970. [Epub ahead of print]
  • Kandasamy M, Roll L, Langenstroth D, Brüstle O, Faissner A (2017). Glycoconjugates reveal diversity of human neural stem cells (hNSCs) derived from human induced pluripotent stem cells (hiPSCs). Cell Tissue Res. 2017 Jun;368(3):531-549. doi: 10.1007/s00441-017-2594-z. Epub 2017 Mar 15.
  • Ulc A, Gottschling C, Schäfer I, Wegrzyn D, van Leeuwen S, Luft V, Reinhard J, Faissner A (2017). Involvement of the guanine nucleotide exchange factor Vav3 in central nervous system development and plasticity. Biol Chem. 2017 May 1;398(5-6):663-675. doi: 10.1515/hsz-2016-0275.
  • Reinhard J, Renner M, Wiemann S, Shakoor DA, Stute G, Dick HB, Faissner A, Joachim SC (2017). Ischemic injury leads to extracellular matrix alterations in retina and optic nerve. Sci Rep. 2017 Mar 6;7:43470. doi: 10.1038/srep43470.

2016

  • Kalbe B, Schulz VM, Schlimm M, Philippou S, Jovancevic N, Jansen F, Scholz P, Lübbert H, Jarocki M, Faissner A, Hecker E, Veitinger S, Tsai T, Osterloh S, Hatt H (2016). Helional-induced activation of human olfactory receptor 2J3 promotes apoptosis and inhibits proliferation in a non-small-cell lung cancer cell line. Eur J Cell Biol. 2016 Dec 5. pii: S0171-9335(16)30281-3. doi: 10.1016/j.ejcb.2016.11.004. [Epub ahead of print]
  • Gottschling C, Dzyubenko E, Geissler M, Faissner A. (2016) The Indirect Neuron-astrocyte Coculture Assay: An In Vitro Set-up for the Detailed Investigation of Neuron-glia Interactions. J Vis Exp. 2016 Nov 14;(117). doi: 10.3791/54757
  • Faissner A, Roll L, Theocharidis U. (2016) Tenascin-C in the matrisome of neural stem and progenitor cells. Mol Cell Neurosci. 2016 Nov 9. pii: S1044-7431(16)30222-6. doi: 10.1016/j.mcn.2016.11.003. [Epub ahead of print] Review.
  • Reinehr S, Reinhard J, Wiemann S, Stute G, Kuehn S, Woestmann J, Dick HB, Faissner A, Joachim SC. (2016) Early remodelling of the extracellular matrix proteins tenascin-C and phosphacan in retina and optic nerve of an experimental autoimmune glaucoma model. J Cell Mol Med. 2016 Nov;20(11):2122-2137. doi: 10.1111/jcmm.12909.
  • Dzyubenko E, Rozenberg A, Hermann DM, Faissner A. (2016) Colocalization of synapse marker proteins evaluated by STED-microscopy reveals patterns of neuronal synapse distribution in vitro. J Neurosci Methods. 2016 Nov 1;273:149-159. doi: 10.1016/j.jneumeth.2016.09.001
  • Gottschling C, Geissler M, Springer G, Wolf R, Juckel G, Faissner A. (2016) First and second generation antipsychotics differentially affect structural and functional properties of rat hippocampal neuron synapses. Neuroscience. 2016 Nov 19;337:117-130. doi: 10.1016/j.neuroscience.2016.08.055
  • Sallouh M, Jarocki M, Sallouh O, Degen P, Faissner A, Weberskirch R. (2016) The Synergistic Effect of Cationic Moieties and GRGDSF-Peptides in Hydrogels on Neural Stem Cell Behavior. Macromol Biosci. 2016 Oct 17. doi: 10.1002/mabi.201600178. [Epub ahead of print]
  • Reinehr S, Reinhard J, Gandej M, Kuehn S, Noristani R, Faissner A, Dick HB, Joachim SC. (2016) Simultaneous Complement Response via Lectin Pathway in Retina and Optic Nerve in an Experimental Autoimmune Glaucoma Model. Front Cell Neurosci. 2016 Jun 1;10:140. doi: 10.3389/fncel.2016.00140
  • Safina D, Schlitt F, Romeo R, Pflanzner T, Pietrzik CU, Narayanaswami V, Edenhofer F, Faissner A. (2016) Low-density lipoprotein receptor-related protein 1 is a novel modulator of radial glia stem cell proliferation, survival, and differentiation. Glia. 2016 Aug;64(8):1363-80. doi: 10.1002/glia.23009
  • Reinhard J, Brösicke N, Theocharidis U, Faissner A. (2016) The extracellular matrix niche microenvironment of neural and cancer stem cells in the brain. Int J Biochem Cell Biol. 2016 Dec;81(Pt A):174-183. doi: 10.1016/j.biocel.2016.05.002. Review.
  • Dzyubenko E, Gottschling C, Faissner A. (2016) Neuron-Glia Interactions in Neural Plasticity: Contributions of Neural Extracellular Matrix and Perineuronal Nets. Neural Plast. 2016;2016:5214961. doi: 10.1155/2016/5214961. Review.
  • Kwiatkowska M, Reinhard J, Roll L, Kraft N, Dazert S, Faissner A, Volkenstein S. Neuroscience (2016) The expression pattern and inhibitory influence of Tenascin-C on the growth of spiral ganglion neurons suggest a regulatory role as boundary formation molecule in the postnatal mouse inner ear. Neuroscience.
  • Karus M, Ulc A, Ehrlich M, Czopka T, Hennen E, Fischer J, Mizhorova M, Qamar N, Brüstle O, Faissner A. (2016) Regulation of oligodendrocyte precursor maintenance by chondroitin sulphate glycosaminoglycans. Glia. 2016 Feb;64(2):270-86. doi: 10.1002/glia.22928.

2015

  • Vogelaar CF, König B, Krafft S, Estrada V, Brazda N, Ziegler B, Faissner A, Müller HW (2015) Pharmacological Suppression of CNS Scarring by Deferoxamine Reduces Lesion Volume and Increases Regeneration in an In Vitro Model for Astroglial-Fibrotic Scarring and in Rat Spinal Cord Injury In Vivo. PLoS One. 2015 Jul 29;10(7):e0134371. doi: 10.1371/journal.pone.0134371. eCollection 2015.
  • Wiese S, Faissner A (2015) The role of extracellular matrix in spinal cord development. Exp Neurol.
  • Vogelaar CF, Konig B, Krafft S, Estrada V, Brazda N, Ziegler B, Faissner A, Muller HW (2015) Pharmacological Suppression of CNS Scarring by Deferoxamine Reduces Lesion Volume and Increases Regeneration in an In Vitro Model for Astroglial-Fibrotic Scarring and in Rat Spinal Cord Injury In Vivo. PLoS One 10:e0134371.
  • Reinhard J, Joachim SC, Faissner A (2015) Extracellular matrix remodeling during retinal development. Experimental eye research 133:132-140.
  • Luft V, Reinhard J, Shibuya M, Fischer KD, Faissner A (2015) Erratum to: The guanine nucleotide exchange factor Vav3 regulates differentiation of progenitor cells in the developing mouse retina. Cell Tissue Res 360:431-433..
  • Luft V, Reinhard J, Shibuya M, Fischer KD, Faissner A (2015) The guanine nucleotide exchange factor Vav3 regulates differentiation of progenitor cells in the developing mouse retina. Cell Tissue Res 359:423-440.
  • Faissner A, Reinhard J (2015) The extracellular matrix compartment of neural stem and glial progenitor cells. Glia 63:1330-1349.
  • Brosicke N, Sallouh M, Prior LM, Job A, Weberskirch R, Faissner A (2015) Extracellular Matrix Glycoprotein-Derived Synthetic Peptides Differentially Modulate Glioma and Sarcoma Cell Migration. Cell Mol Neurobiol 35:741-753.
  • Brosicke N, Faissner A (2015) Role of tenascins in the ECM of gliomas. Cell Adh Migr 9:131-140.

2014

  • Theocharidis U, Long K, Ffrench-Constant C, Faissner A (2014) Regulation of the neural stem cell compartment by extracellular matrix constituents. Progress in brain research 214:3-28.
  • Roll L, Faissner A (2014) Influence of the extracellular matrix on endogenous and transplanted stem cells after brain damage. Frontiers in cellular neuroscience 8:219.
  • Reinhard J, Joachim SC, Faissner A (2014) Extracellular matrix remodeling during retinal development. Experimental eye research.
  • Luft V, Reinhard J, Shibuya M, Fischer KD, Faissner A (2014) The guanine nucleotide exchange factor Vav3 regulates differentiation of progenitor cells in the developing mouse retina. Cell Tissue Res.
  • Hennen E, Faissner A (2014) Modulation of neural stem cell expressed ECM by targeting glycosyltransferases. In: Neuromethods 93, Extracellular Matrix, chapter 13 (Leach, J. B. and Powell, E. M., eds), pp 151-160: Humana Press, Springer Science and Business media.
  • Heikkinen A, Pihlajaniemi T, Faissner A, Yuzaki M (2014) Neural ECM and synaptogenesis. Progress in brain research 214:29-51.
  • Conrad R, Klausmeyer A, Tsai T, Faissner A, Wiese S (2014) Extracellular matrix components as a substrate of outgrowing motoneurons. In: Neuromethods 93, Extracellular Matrix, chapter 7 (Leach, J. B. and Powell, E. M., eds), pp 67-78: Humana Press, Springer Science and Business media.

2013

  • Pachernegg S, Joshi I, Muth-Kohne E, Pahl S, Munster Y, Terhag J, Karus M, Werner M, Ma-Hogemeier ZL, Korber C, Grunwald T, Faissner A, Wiese S, Hollmann M (2013) Undifferentiated embryonic stem cells express ionotropic glutamate receptor mRNAs. Frontiers in cellular neuroscience 7:241.
  • Brosicke N, van Landeghem FK, Scheffler B, Faissner A (2013) Tenascin-C is expressed by human glioma in vivo and shows a strong association with tumor blood vessels. Cell Tissue Res 354:409-430.
  • Tsai T, Klausmeyer A, Conrad R, Gottschling C, Leo M, Faissner A, Wiese S (2013) 7,8-Dihydroxyflavone leads to survival of cultured embryonic motoneurons by activating intracellular signaling pathways. Mol Cell Neurosci 56C:18-28.
  • Pacharra S, Hanisch FG, Muhlenhoff M, Faissner A, Rauch U, Breloy I (2013) The Lecticans of Mammalian Brain Perineural Net Are O-Mannosylated. Journal of proteome research 12:1764-1771.
  • Karus M, Hennen E, Safina D, Klausmeyer A, Wiese S, Faissner A (2013) Differential Expression of Micro-Heterogeneous LewisX-Type Glycans in the Stem Cell Compartment of the Developing Mouse Spinal Cord. Neurochemical research 38:1285-1294.
  • Hennen E, Safina D, Haussmann U, Worsdorfer P, Edenhofer F, Poetsch A, Faissner A (2013) A LewisX-glycoprotein screen identifies the low density lipoprotein receptor-related protein 1 (LRP1) as a modulator of oligodendrogenesis in mice. J Biol Chem. 288:16538-16545.
  • Geissler M, Gottschling C, Aguado A, Rauch U, Wetzel CH, Hatt H, Faissner A (2013) Primary hippocampal neurons, which lack four crucial extracellular matrix molecules, display abnormalities of synaptic structure and function and severe deficits in perineuronal net formation. J Neurosci 33:7742-7755.

2012

  • Wiese S, Karus M, Faissner A (2012) Astrocytes as a source for extracellular matrix molecules and cytokines. Frontiers in pharmacology 3:120.
  • Tsai T, Karus M, Faissner A, Wiese S (2012) Wie aus neuralen Stammzellen gezielt Nervenzellen werden. BIOforum 2/2012:2-4.
  • Theocharidis U, Faissner A (2012) Analysis of alternatively spliced domains in multimodular gene products – the extracellular matix glycoprotein tenascin C. In: Polymerase Chain Reaction (Hernandez-Rodriguez P, ed): InTech, Chapter 23, 487-500.
  • Roll L, Mittmann T, Eysel UT, Faissner A (2012) The laser lesion of the mouse visual cortex as a model to study neural extracellular matrix remodeling during degeneration, regeneration and plasticity of the CNS.Cell Tissue Res 349:133-145.
  • Purushothaman A, Sugahara K, Faissner A (2012) Chondroitin sulfate "wobble motifs" modulate maintenance and differentiation of neural stem cells and their progeny. J Biol Chem 287:2935-2942.
  • Faissner A (2012) Neuron Migration and Axon Guidance. In: Neuroglia 3rd Edition (Kettenmann, H. and Ransom, B. R., eds), pp 402-416: Oxford University Press.
  • Karus M, Samtleben S, Busse C, Tsai T, Dietzel ID, Faissner A, Wiese S (2012) Normal Sulphation levels regulate spinal cord neural precursor cell proliferation and differentiation. Neural Dev 7:20.
  • Hennen E, Faissner A (2012) LewisX: a neural stem cell specific glycan? Int J Biochem Cell Biol 44:830-833.
  • Geissler M, Faissner A (2012) A new indirect co-culture set up of mouse hippocampal neurons and cortical astrocytes on microelectrode arrays. J Neurosci Methods 204:262-272.
  • Garwood J, Theocharidis U, Calco V, Dobbertin A, Faissner A (2012) Existence of Tenascin-C Isoforms in Rat that Contain the Alternatively Spliced AD1 Domain are Developmentally Regulated During Hippocampal Development. Cell Mol Neurobiol 32:279-287.
  • Besser M, Jagatheaswaran M, Reinhard J, Schaffelke P, Faissner A (2012) Tenascin C regulates proliferation and differentiation processes during embryonic retinogenesis and modulates the de-differentiation capacity of Muller glia by influencing growth factor responsiveness and the extracellular matrix compartment. Dev Biol 369:163-176.
  • Thöne J, Ellrichmann G, Seubert S, Peruga I, Lee DH, Conrad R, Hayardeny L, Comi G, Wiese S, Linker RA, Gold R. Modulation of autoimmune demyelination by laquinimod via induction of brain-derived neurotrophic factor. Am J Pathol. 2012 Jan;180(1):267-74.
  • Gorboulev V, Schürmann A, Vallon V, Kipp H, Jaschke A, Klessen D, Friedrich A, Scherneck S, Rieg T, Cunard R, Veyhl-Wichmann M, Srinivasan A, Balen D, Breljak D, Rexhepaj R, Parker HE, Gribble FM, Reimann F, Lang F, Wiese S, Sabolic I, Sendtner M, Koepsell H. Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion. Diabetes. 2012 Jan;61(1):187-96.

2011

  • Karus M, Denecke B, ffrench-Constant C, Wiese S, Faissner A (2011) The extracellular matrix molecule tenascin-C modifies expression levels and territories of key patterning genes during spinal cord astrocyte specification. Development 138: 5321-5331
  • Pyka M, Wetzel C, Aguado A, Geissler M, Hatt H, Faissner A (2011) Chondroitin sulfate proteoglycans regulate astrocyte-dependent synaptogenesis and modulate synaptic activity in primary embryonic hippocampal neurons. Eur J Neurosci 33:2187-2202.
  • Pyka M, Busse C, Seidenbecher C, Gundelfinger ED, Faissner A (2011) Astrocytes are crucial for survival and maturation of embryonic hippocampal neurons in a neuron-glia cell-insert coculture assay. Synapse 65:41-53.
  • Klausmeyer A, Conrad R, Faissner A, Wiese S (2011) Influence of glial-derived matrix molecules, especially chondroitin sulfates, on neurite growth and survival of cultured mouse embryonic motoneurons. J Neurosci Res 89:127-141.
  • Hennen E, Czopka T, Faissner A (2011) Structurally Distinct LewisX Glycans Distinguish Subpopulations of Neural Stem/Progenitor Cells. J Biol Chem 286:16321-16331.
  • Bockelmann J, Klinkhammer K, von Holst A, Seiler N, Faissner A, Brook GA, Klee D, Mey J (2011) Functionalization of Electrospun Poly(epsilon-Caprolactone) Fibers with the Extracellular Matrix-Derived Peptide GRGDS Improves Guidance of Schwann Cell Migration and Axonal Growth. Tissue Eng Part A 17(3-4) 475-486.
  • Conrad R, Jablonka S, Sczepan T, Sendtner M, Wiese S, Klausmeyer A. Lectin-based isolation and culture of mouse embryonic motoneurons. J Vis Exp. 2011 Sep 15;(55).
  • Linker RA, Lee DH, Ryan S, van Dam AM, Conrad R, Bista P, Zeng W, Hronowsky X, Buko A, Chollate S, Ellrichmann G, Brück W, Dawson K, Goelz S, Wiese S, Scannevin RH, Lukashev M, Gold R. Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway. Brain. 2011 Mar;134(Pt 3):678-92.
  • Klausmeyer A, Conrad R, Faissner A, Wiese S. Influence of glial-derived matrix molecules, especially chondroitin sulfates, on neurite growth and survival of cultured mouse embryonic motoneurons. J Neurosci Res. 2011 Feb;89(2):127-41.

2010

  • Sirko S, von Holst A, Weber A, Wizenmann A, Theocharidis U, Gotz M, Faissner A (2010) Chondroitin sulfates are required for fibroblast growth factor-2-dependent proliferation and maintenance in neural stem cells and for epidermal growth factor-dependent migration of their progeny. Stem Cells 28:775-787.
  • Sirko S, Akita K, Von Holst A, Faissner A (2010) Structural and functional analysis of chondroitin sulfate proteoglycans in the neural stem cell niche. Methods Enzymol 479:37-71.
  • Muth-Kohne E, Pachernegg S, Karus M, Faissner A, Hollmann M (2010) Expression of NMDA receptors and Ca2+-impermeable AMPA receptors requires neuronal differentiation and allows discrimination between two different types of neural stem cells. Cell Physiol Biochem 26:935-946.
  • Faissner A, Pyka M, Geissler M, Sobik T, Frischknecht R, Gundelfinger ED, Seidenbecher C (2010) Contributions of astrocytes to synapse formation and maturation - Potential functions of the perisynaptic extracellular matrix. Brain Res Rev 63:26-38.
  • Dobbertin A, Czvitkovich S, Theocharidis U, Garwood J, Andrews MR, Properzi F, Lin R, Fawcett JW, Faissner A (2010) Analysis of combinatorial variability reveals selective accumulation of the fibronectin type III domains B and D of tenascin-C in injured brain. Exp Neurol 225:60-73.
  • Czopka T, von Holst A, ffrench-Constant C, Faissner A (2010) Regulatory mechanisms that mediate tenascin C-dependent inhibition of oligodendrocyte precursor differentiation. J Neurosci 30:12310-12322.
  • Afshari FT, Kwok JC, Andrews MR, Blits B, Martin KR, Faissner A, Ffrench-Constant C, Fawcett JW (2010) Integrin activation or alpha 9 expression allows retinal pigmented epithelial cell adhesion on Bruch's membrane in wet age-related macular degeneration. Brain 133:448-464.
  • Linker RA, Lee D, Demir S, Wiese S, Kruse N, Siglienti I, Gerhardt E, Neumann H, Sendtner M, Lühder F, Gold R. (2010) Functional role of brain-derived neurotrophic factor in neuroprotective autoimmunity: therapeutic implications in a model of multiple sclerosis. Brain Aug; 133: 2248-2263.
  • Rauskolb S, Zagrebelsky M, Dreznjak A, Deogracias R, Matsumoto T, Wiese S, Erne B, Sendtner M, Schaeren-Wiemers N, Korte M, Barde YA. (2010) Global deprivation of brain-derived neurotrophic factor in the CNS reveals an area-specific requirement for dendritic growth. J Neurosci. Feb 3;30(5):1739-49.

2009

  • von Holst A, Faissner A (2009) Im gemachten Nest – Struktur und Funktionen neuraler Stammzellnischen / Pampered in the nest – Structure and Functions of Neural Stem Cell Niches. Neuroforum XV:44 - 55.
  • Sirko S, Neitz A, Mittmann T, Horvat-Brocker A, von Holst A, Eysel UT, Faissner A (2009) Focal laser-lesions activate an endogenous population of neural stem/progenitor cells in the adult visual cortex. Brain 132:2252-2264.
  • Siddiqui S, Horvat-Broecker A, Faissner A (2009) Comparative screening of glial cell types reveals extracellular matrix that inhibits retinal axon growth in a chondroitinase ABC-resistant fashion. Glia 57:1420-1438.
  • Robel S, Mori T, Zoubaa S, Schlegel J, Sirko S, Faissner A, Goebbels S, Dimou L, Gotz M (2009) Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis. Glia 57:1630-1647.
  • Reinhard J, Horvat-Brocker A, Illes S, Zaremba A, Knyazev P, Ullrich A, Faissner A (2009) Protein tyrosine phosphatases expression during development of mouse superior colliculus. Exp Brain Res 199:279-297.
  • Michele M, Faissner A (2009) Tenascin-C stimulates contactin-dependent neurite outgrowth via activation of phospholipase C. Mol Cell Neurosci 41:397-408.
  • Faissner A (2009) Axon guidance. In: Neuroglia, 2nd Edition (Kettenmann H, Ransom BR, eds), p Chapter 32. Oxford: Oxford Scholarship Online (http://www.oxfordscholarship.com/).
  • Faissner A (2009) Axon guidance by glia. In: Developmental Neurobiology (Lemke G, ed), pp 393-402: Academic Press
  • Faissner A (2009) Axon guidance by glia [Article 1758]. In: Encyclopedia of Neuroscience (Squire LR, ed), pp 1063-1072: Oxford: Academic Press.
  • Czopka T, Von Holst A, Schmidt G, Ffrench-Constant C, Faissner A (2009) Tenascin C and tenascin R similarly prevent the formation of myelin membranes in a RhoA-dependent manner, but antagonistically regulate the expression of myelin basic protein via a separate pathway. Glia 57:1790-1801.
  • Czopka T, Hennen E, von Holst A, Faissner A (2009) Novel conserved oligodendrocyte surface epitope identified by monoclonal antibody 4860. Cell Tissue Res 338:161-170.
  • Besser M, Horvat-Bröcker A, Eysel UT, Faissner A (2009) Differential expression of receptor protein tyrosine phosphatases accompanies the reorganisation of the retina upon laser lesion. Exp Brain Res 198:37-47.
  • Andrews MR, Czvitkovich S, Dassie E, Vogelaar CF, Faissner A, Blits B, Gage FH, ffrench-Constant C, Fawcett JW (2009) Alpha9 integrin promotes neurite outgrowth on tenascin-C and enhances sensory axon regeneration. J Neurosci 29:5546-5557.
  • Strelau J, Strzelczyk A, Rusu P, Bendner G, Wiese S, Diella F, Altick AL, von Bartheld CS, Klein R, Sendtner M, Unsicker K. (2009) Progressive postnatal motoneuron loss in mice lacking GDF-15. J Neurosci. Oct 28;29(43):13640-8.
  • Trimbuch T, Beed P, Vogt J, Schuchmann S, Maier N, Kintscher M, Breustedt J, Schuelke M, Streu N, Kieselmann O, Brunk I, Laube G, Strauss U, Battefeld A, Wende H, Birchmeier C, Wiese S, Sendtner M, Kawabe H, Kishimoto-Suga M, Brose N, Baumgart J, Geist B, Aoki J, Savaskan NE, Bräuer AU, Chun J, Ninnemann O, Schmitz D, Nitsch R. (2009) Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling. Cell. Sep 18;138(6):1222-35.

2008

  • Siddiqui S, Horvat-Brocker A, Faissner A (2008) The glia-derived extracellular matrix glycoprotein tenascin-C promotes embryonic and postnatal retina axon outgrowth via the alternatively spliced fibronectin type III domain TNfnD. Neuron Glia Biol 4:271-283.
  • Moritz S, Lehmann S, Faissner A, von Holst A (2008) An induction gene trap screen in neural stem cells reveals an instructive function of the niche and identifies the splicing regulator sam68 as a tenascin-C-regulated target gene. Stem Cells 26:2321-2331.
  • Horvat-Brocker A, Reinhard J, Illes S, Paech T, Zoidl G, Harroch S, Distler C, Knyazev P, Ullrich A, Faissner A (2008) Receptor protein tyrosine phosphatases are expressed by cycling retinal progenitor cells and involved in neuronal development of mouse retina. Neuroscience 152:618-645.
  • Akita K, von Holst A, Furukawa Y, Mikami T, Sugahara K, Faissner A (2008) Expression of multiple chondroitin/dermatan sulfotransferases in the neurogenic regions of the embryonic and adult central nervous system implies that complex chondroitin sulfates have a role in neural stem cell maintenance. Stem Cells 26:798-809.

2007

  • von Holst A, Egbers U, Prochiantz A, Faissner A (2007) Neural stem/progenitor cells express 20 tenascin C isoforms that are differentially regulated by Pax6. J Biol Chem 282:9172-9181.
  • Sirko S, von Holst A, Wizenmann A, Gotz M, Faissner A (2007) Chondroitin sulfate glycosaminoglycans control proliferation, radial glia cell differentiation and neurogenesis in neural stem/progenitor cells. Development 134:2727-2738.
  • Klausmeyer A, Garwood J, Faissner A (2007) Differential expression of phosphacan/RPTPbeta isoforms in the developing mouse visual system. J Comp Neurol 504:659-679.
  • Kazanis I, Belhadi A, Faissner A, Ffrench-Constant C (2007) The adult mouse subependymal zone regenerates efficiently in the absence of tenascin-C. J Neurosci 27:13991-13996.
  • Heck N, Garwood J, Dobbertin A, Calco V, Sirko S, Mittmann T, Eysel UT, Faissner A (2007) Evidence for distinct leptomeningeal cell-dependent paracrine and EGF-linked autocrine regulatory pathways for suppression of fibrillar collagens in astrocytes. Mol Cell Neurosci 36:71-85.
  • Wiese S, Jablonka S, Holtmann B, Orel N, Rajagopal R, Chao MV, Sendtner M. Adenosine receptor A2A-R contributes to motoneuron survival by transactivating the tyrosine kinase receptor TrkB. Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):17210-5.
  • Frebel K, Wiese S, Funk N, Sendtner M. Differential Modulation of Neurite Growth by the S- and the L-Forms of bag1, a Co-Chaperone of Hsp70. Neurodegener Dis. 2007;4(2-3):261-9.
  • Fischer A, Hekman M, Kuhlmann J, Rubio I, Wiese S, Rapp UR. B- and C-RAF display essential differences in their binding to Ras: the isotype-specific N terminus of B-RAF facilitates Ras binding. J Biol Chem. 2007 Sep 7;282(36):26503-16.

2006

  • von Holst A, Sirko S, Faissner A (2006) The unique 473HD-Chondroitinsulfate Epitope is Expressed by Radial Glia and Involved in Neural Precursor Cell Proliferation. Journal of Neuroscience 26:4082-4094.
  • Faissner A, Heck N, Dobbertin A, Garwood J (2006) DSD-1-Proteoglycan/Phosphacan and receptor protein tyrosine phosphatase-beta isoforms during development and regeneration of neural tissues. Adv Exp Med Biol 557:25-53.
  • Frebel K, Wiese S. Signalling molecules essential for neuronal survival and differentiation.Biochem Soc Trans. 2006 Dec;34(Pt 6):1287-90. Review.
  • Camarero G, Tyrsin OY, Xiang C, Pfeiffer V, Pleiser S, Wiese S, Gotz R, Rapp UR. Cortical migration defects in mice expressing A-RAF from the B-RAF locus. Mol Cell Biol. 2006 Oct;26(19):7103-15.
  • Ito Y, Wiese S, Funk N, Chittka A, Rossoll W, Bommel H, Watabe K, Wegner M, Sendtner M. Sox10 regulates ciliary neurotrophic factor gene expression in Schwann cells. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7871-6.
  • Hekman M, Albert S, Galmiche A, Rennefahrt UE, Fueller J, Fischer A, Puehringer D, Wiese S, Rapp UR. Reversible membrane interaction of BAD requires two C-terminal lipid binding domains in conjunction with 14-3-3 protein binding. J Biol Chem. 2006 Jun 23;281(25):17321-36.

2005

  • Ito Y, Hikino M, Yajima Y, Mikami T, Sirko S, von Holst A, Faissner A, Fukui S, Sugahara K (2005) Structural characterization of the epitopes of the monoclonal antibodies 473HD, CS-56, and MO-225 specific for chondroitin sulfate D-type using the oligosaccharide library. Glycobiology 15:593-603.
  • Heck N, Klausmeyer A, Faissner A, Garwood J (2005) Cortical neurons express PSI, a novel isoform of phosphacan/RPTPbeta. Cell Tissue Res 321:323-333.
  • Faissner A, Heck N, Dobbertin A, Garwood J (2005) DSD-1-Proteoglycan/Phosphacan and Receptor Protein Tyrosine Phosphatase-Beta Isoforms during Development and Regeneration of Neural Tissues. In: Brain Repair (Bahr M, ed): Plenum Publishers Corporation.
  • Faissner A (2005) Axon guidance. In: Neuroglia, Second Edition Edition (Kettenmann H, Ransom BR, eds), pp 405-417. Oxford • New York: Oxford University Press.
  • Bao X, Mikami T, Yamada S, Faissner A, Muramatsu T, Sugahara K (2005) Heparin-binding growth factor, pleiotrophin, mediates neuritogenic activity of embryonic pig brain-derived chondroitin sulfate/dermatan sulfate hybrid chains. J Biol Chem 280:9180-9191.

2004

  • Heck N, Garwood J, Loeffler JP, Larmet Y, Faissner A (2004) Differential upregulation of extracellular matrix molecules associated with the appearance of granule cell dispersion and mossy fiber sprouting during epileptogenesis in a murine model of temporal lobe epilepsy. Neuroscience 129:309-324.
  • Garwood J, Garcion E, Dobbertin A, Heck N, Calco V, ffrench-Constant C, Faissner A (2004) The extracellular matrix glycoprotein Tenascin-C is expressed by oligodendrocyte precursor cells and required for the regulation of maturation rate, survival and responsiveness to platelet-derived growth factor. Eur J Neurosci 20:2524-2540.
  • Garcion E, Halilagic A, Faissner A, ffrench-Constant C (2004) Generation of an environmental niche for neural stem cell development by the extracellular matrix molecule tenascin C. Development 131:3423-3432.
  • Camand E, Morel MP, Faissner A, Sotelo C, Dusart I (2004) Long-term changes in the molecular composition of the glial scar and progressive increase of serotoninergic fibre sprouting after hemisection of the mouse spinal cord. Eur J Neurosci 20:1161-1176.

2003

  • Hikino M, Mikami T, Faissner A, Vilela-Silva AC, Pavao MS, Sugahara K (2003) Oversulfated dermatan sulfate exhibits neurite outgrowth-promoting activity toward embryonic mouse hippocampal neurons: implications of dermatan sulfate in neuritogenesis in the brain. J Biol Chem 278:43744-43754.
  • Heck N, Garwood J, Schutte K, Fawcett J, Faissner A (2003) Astrocytes in culture express fibrillar collagen. Glia 41:382-392.
  • Garwood J, Heck N, Reichardt F, Faissner A (2003) Phosphacan short isoform, a novel non-proteoglycan variant of phosphacan/receptor protein tyrosine phosphatase-beta, interacts with neuronal receptors and promotes neurite outgrowth. J Biol Chem 278:24164-24173.
  • Faissner A (2003) Räume der Begegnung: wo Nervenbahnen entstehen, wachsen und sich verändern. Rubin Sonderheft 2003:41-45.
  • Dobbertin A, Rhodes KE, Garwood J, Properzi F, Heck N, Rogers JH, Fawcett JW, Faissner A (2003) Regulation of RPTPbeta/phosphacan expression and glycosaminoglycan epitopes in injured brain and cytokine-treated glia. Mol Cell Neurosci 24:951-971.

2002

  • Rigato F, Garwood J, Calco V, Heck N, Faivre-Sarrailh C, Faissner A (2002) Tenascin-C promotes neurite outgrowth of embryonic hippocampal neurons through the alternatively spliced fibronectin type III BD domains via activation of the cell adhesion molecule F3/contactin. J Neurosci 22:6596-6609.
  • Garcion E, Faissner A, ffrench-Constant C (2002) La ténascine-C: une molécule de la matrice extracellulaire impliquée dans le développement du système nerveux central. Medecine Sciences 18:982-988.

2001

  • Riedl S, Tandara A, Reinshagen M, Hinz U, Faissner A, Bodenmuller H, Buhr HJ, Herfarth C, Moller P (2001) Serum tenascin-C is an indicator of inflammatory bowel disease activity. Int J Colorectal Dis 16:285-291.
  • Joester A, Faissner A (2001) The structure and function of tenascins in the nervous system. Matrix Biol 20:13-22.
  • Garwood J, Rigato F, Heck N, Faissner A (2001) Tenascin glycoproteins and the complementary ligand DSD-1-PG/ phosphacan--structuring the neural extracellular matrix during development and repair. Restor Neurol Neurosci 19:51-64.
  • Garwood J, Heck N, Rigato F, Faissner A (2001) The extracellular Matrix in neural Development, Plasticity and Regeneration. In: Neural Environment, The Brain Homeostasis in Health and Disease (Walz W, ed), pp 109-158. Totowa NJ: Humana Press.
  • Garcion E, Faissner A, ffrench-Constant C (2001) Knockout mice reveal a contribution of the extracellular matrix molecule tenascin-C to neural precursor proliferation and migration. Development 128:2485-2496.
  • Adamsky K, Schilling J, Garwood J, Faissner A, Peles E (2001) Glial tumor cell adhesion is mediated by binding of the FNIII domain of receptor protein tyrosine phosphatase beta (RPTPbeta) to tenascin C. Oncogene 20:609-618.

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