Selected Publications
| Molitor, B., Stassen, M., Modi, A., El-Mashtoly, S.F., Laurich, C., Lubitz, W., Dawson, J.H., Rother, M., & Frankenberg-Dinkel, N. (2013) A heme-based redox sensor in the methanogenic archaeon Methanosarcina acetivorans. J. Biol. Chem. In press | PubMed |
| Salewski, J., Velazquez, F., Kaminski, S., von Stetten, D., Keidel, A., Rippers, Y., Michael, N., Scheerer, P., Piwowarski, P., Bartl, F., Frankenberg-Dinkel, N., Ringsdorf, S., Gärtner, W., Lamparter, T., Mroginski, M.A. & Hildebrandt, P. (2013) The structure of the biliverdin cofactor in the Pfr state of bathy and prototypical phytochromes. J. Biol. Chem. In press | PubMed |
| Shah, R., Schwach, J., Frankenberg-Dinkel, N. & Gärtner, W. (2012) Complex formation between heme oxygenase and phytochrome during biosynthesis in Pseudomonas syringae pv tomato. Photochem. Photobiol. Sci. 11, 1026-1031. | PubMed |
| Wallner, T., Hagiwara, Y., Sobotka, R., Bernát, G., Reijerse, E.J., Frankenberg- Dinkel, N. & Wilde, A. (2012) Inactivation of the conserved open reading frame ycf34 of Synechocystis sp. PCC 6803 interferes with the photosynthetic electron transport chain. Biochim. Biophys. Acta-Bioenergetics im Druck | PubMed |
| Gisk, B., Wiethaus, J., Aras, M. & Frankenberg-Dinkel, N. (2012) Variable composition of heme oxygenases with different regiospecificities in Pseudomonas species. Arch. Microbiol. 194, 597-606. | PubMed |
| Gisk, B., Molitor, B., Frankenberg-Dinkel, N. & Kötting, C. (2012) Heme oxygenases from Arabidopsis thaliana reveal different mechanisms of carbon monoxide binding. Spectrochim. Acta A: Mol. Biomol. Spectroscopy 88, 235-240. | PubMed |
| Busch, A.W.U, Reijerse, E.J., Lubitz, W, Frankenberg-Dinkel, N.*& Hofmann, E.* (2011) Structural and mechanistic insights into the two-electron reduction of bilins Biochem. J. 439, 264-257. *corresponding author |
PubMed |
| Barkovits, K., Schubert, B., Heine, S., Scheer, M. & Frankenberg-Dinkel, N. (2011) Function of the bacteriophytochrome BphP in the RpoS/Las-Quorum sensing network of Pseudomonas aeruginosa. Microbiology 157, 1651-64. | PubMed |
| Busch A.W., Reijerse, E.J., Lubitz, W., Hofmann, E., Frankenberg-Dinkel, N. (2011) Radical mechanism of cyanophage phycoerythrobilin synthase (PebS) Biochem. J. 14;433(3):469-76 | PubMed |
| Gisk B, Brégier F, Krüger RA, Bröring M, Frankenberg-Dinkel N. (2010) Enzymatic Ring Opening of an Iron Corrole by Plant-Type Heme Oxygenases: Unexpected Substrate and Protein Selectivities. Biochemistry 30;49(47):10042-4. | PubMed |
| Wiethaus J., Busch A.W., Dammeyer T., Frankenberg-Dinkel N. (2010) Phycobiliproteins in Prochlorococcus marinus: Biosynthesis of pigments and their assembly into proteins. European Journal of Cell Biology 89 1005–1010 | PubMed |
| Wiethaus, J., Busch, A.W., Kock, K., Leichert, L.I., Herrmann, C. & Frankenberg-Dinkel N.(2010) CpeS is a lyase specific for attachment of 3Z-PEB to Cys82 of b-phycoerythrin from Prochlorococcus marinus MED4. J. Biol. Chem. 26;285(48):37561-9. | PubMed |
| Gisk, B., Yasui, Y., Kohchi, T. & Frankenberg-Dinkel, N. (2010) Characterization of the heme oxygenase protein family in Arabidopsis thaliana reveals a diversity of functions. Biochem J. 425, 425-434. |
PubMed |
| Michel, K.-P.., Schröder, A.-K., Zimmermann, M.,Brandt, S.,Pistorius, E.K., Frankenberg-Dinkel, N..& Staiger, D. (2009) The hybrid histidine kinase Slr 1759 of the cyanobacterium Synechocystis sp. PCC 6803 contains FAD as a cofactor at its PAS domain. Arch. Microbiol. 191, 553-559 |
PubMed |
| Brandt, S., von Stetten, D., Günther, M., Hildebrandt, P. & Frankenberg-Dinkel, N. (2008) The fungal phytochrome FphA from Aspergillus nidulans. J. Biol. Chem. 283, 34605-34614. |
PubMed |
| Dammeyer, T. & Frankenberg-Dinkel, N. (2008) Function and distribution of bilin biosynthesis enzymes in photosynthetic organisms. Photochem Photobiol Sci. 7, 71121-71130. |
PubMed |
| Dammeyer, T., Hofmann, E. & Frankenberg-Dinkel, N. (2008) Phycoerythrobilin synthase (PebS) of a marine virus- Crystal structures of the biliverdin-complex and the substrate free form. J. Biol. Chem. 283, 27547-27554 |
PubMed |
| Dammeyer, T., Bagby, S.C., Sullivan, M.B., Chisholm, S.W. & Frankenberg-Dinkel, N. (2008) Efficient Phage-Mediated Pigment Biosynthesis in Oceanic Cyanobacteria Curr. Biol. 18, 442-448 |
PubMed |
| Barkovits, K., Harms, A., Benkartek, C., Smart, J. L. & Frankenberg- Dinkel, N. (2008) Expression of the Pseudomonas aeruginosa phytochrome operon is dependent on the alternative sigma factor RpoS. FEMS Microbiol. Lett. 280, 160-168. |
PubMed |
| Brandt, S. & Frankenberg-Dinkel, N. (2007) Phytochrome: Bakterien sehen Rot. Biospektrum 4, 358-360. |
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| Dammeyer, T., Michaelsen, K. & Frankenberg-Dinkel, N. (2007) Biosynthesis of open chain tetrapyrroles in Prochlorococcus marinus. FEMS Microbiol Lett., 271, 251-257. |
PubMed |
| Alvey, R. M., Bezy, R. P., Frankenberg-Dinkel, N. & Kehoe, D.M. (2007) A light-regulated OmpR-class promoter element coordinates light harvesting protein and chromophore biosynthetic enzyme gene expression Mol. Microbiol. 64, 319-332. |
PubMed |
| Gacond, S., Frère, F., Nentwich, M., Faurite, J.-P., Frankenberg-Dinkel, N. & Neier, R. (2007) Synthesis of Bisubstrate Inhibitors of Porphobilinogen Synthase from Pseudomonas aeruginosa. Chem. Biodiv.,4, 189-202. |
PubMed |
| Dammeyer, T. & Frankenberg-Dinkel, N.(2006) Insights into phycoerythrobilin biosynthesis point towards for metabolic channeling. J. Biol. Chem. 281, 27081-27089 |
PubMed |
| Frere, F., Nentwich, M., Gacond, S., Heinz, D.W., Neier, R. & Frankenberg-Dinkel, N. (2006) Probing the active site of Pseudomonas aeruginosa porphobilinogen synthase using newly developed inhibitors Biochemistry, 45, 8243 -8253. |
PubMed |
| Blumenstein, A., Vienken, K., Tasler, R., Purschwitz, J., Veith, D., Frankenberg-Dinkel, N. & Fischer, R. (2005)The Aspergillus nidulans phytochrome FphA represses sexual development in red light. Curr. Biol. , 15, 1833-1838. |
PubMed |
| Steglich, C., Frankenberg-Dinkel, N., Penno, S. & Hess, W. R. (2005) An unusual green light-absorbing phycoerythrin evolved in the high-light-adapted marine cyanobacterium Prochlorococcus sp. MED4. Environ. Microbiol 7, 1611-1618. |
PubMed |
| Tasler, R., Moises, T. & Frankenberg-Dinkel, N. (2005) Biochemical and spectroscopic characterization of the bacterial phytochrome of Pseudomonas aeruginosa. FEBS J. 272, 1927-1936 . |
PubMed |
| Wegele, R., Tasler, R., Zeng, Y., Rivera, M. & Frankenberg-Dinkel, N. (2004) The hemeoxygenase(s)-phytochrome system of Pseudomonas aeruginosa. J. Biol. Chem. 279, 45791-45802. |
PubMed |
| Frankenberg, N. & Lagarias, J. C. (2003) Phycocyanobilin:ferredoxin oxidoreductase (PcyA) of Anabaena sp. PCC 7120. Biochemical and spectroscopic characterization. J. Biol. Chem. 278, 9219-9226. |
PubMed |
| Frère, F., Schubert, W. D., Stauffer, F., Frankenberg, N., Neier, R., Jahn, D. & Heinz, D.W. (2002) Structure of porphobilinogen synthase from Pseudomonas aeruginosa in complex with 5-fluorolevulinic acid suggests a double Schiff base mechanism. J. Mol. Biol. 320, 237-247. |
PubMed |
| Kohchi, T., Mukougawa, K., Frankenberg, N., Masuda, M., Yokota, A. & Lagarias, J.C. (2001) The Arabidopsis HY2 gene encodes a ferredoxin-dependent phytochromobilin synthase for phytochrome chromophore biosynthesis. Plant Cell Physiol . 42 (supplement: s 56) |
PubMed |
| Frankenberg, N., Mukougawa, K., Kohchi, T. & Lagarias, J.C. (2001) Functional genomic characterization of the HY2 family of ferredoxin-dependent bilin reductases from oxygenic photosynthetic bacteria. Plant Cell 13, 965-978. |
PubMed |
| Kohchi, T., Mukougawa, K., Frankenberg, N., Masuda, M., Yokota, A. & Lagarias, J.C. (2001) The Arabidopsis HY2 gene, necessary for phytochrome chromophore biosynthesis, encodes phytochromobilin synthase. Plant Cell 13, 425-436. | PubMed |