Faculty of chemistry and biochemistry » Workgroup Dr. Ebbinghaus

Publications



Imperfect crowding adaptation of mammalian cells towards osmotic stress and its modulation by osmolytes

D. Gnutt, O. Brylski, E. Edengeiser, M. Havenith, S. Ebbinghaus*
Molecular BioSystems, 2017, accepted, DOI: 10.1039/C7MB00432J


Elucidation of the Catalytic Mechanism of a Miniature Zinc Finger Hydrolase

A. Ganguly, T. Luong, O. Brylski, M. Dirkmann, D. Möller, S. Ebbinghaus, F. Schulz, R. Winter, E. Sanchez-Garcia*, W. Thiel*
Journal of Physical Chemistry B, 21(26):6390–6398, 2017.


Inhibition of Huntingtin Exon‑1 Aggregation by the Molecular Tweezer CLR01

T. Vöpel, K. Bravo-Rodriguez, S. Mittal, S. Vachharajani, D. Gnutt, A. Sharma, A. Steinhof, O. Fatoba, G. Ellrichmann, M. Nshanian, C. Heid, J. A. Loo, F. G. Klärner, T. Schrader, G. Bitan, E. E. Wanker,
S. Ebbinghaus*, E. Sanchez-Garcia*
J. Am. Chem. Soc., 139(16):5640–5643, 2017.


Conformational dynamics and self-association of intrinsically disordered Huntingtin exon 1 in cells

S. Büning, A. Sharma, S. Vachharajani, E. Newcombe, A. Ormsby, M. Gao, D. Gnutt, T. Vöpel, D. M. Hatters, S. Ebbinghaus*
Phys. Chem. Chem. Phys., 19, 10738-10747, 2017.


Das Innere der Zelle: Ein komplexes Lösungsmittel

M. Heyden, S. Ebbinghaus, R. Winter
Chemie in unserer Zeit, 51(1), 26–33, 2017.


The Temperature Dependence of the Hofmeister Series: Thermodynamic Fingerprints of Cosolute-Protein Interactions

M. Senske, D. Constantinescu, M. Havenith, C. Herrmann*, H. Weingärtner, S. Ebbinghaus*
Phys. Chem. Chem. Phys., 18, 29698-29708, 2016.


RNA hairpin folding in the crowded cell

M. Gao#, D. Gnutt#, A. Orban, B. Appel, F. Righetti, R. Winter, F. Narberhaus, S. Müller, S. Ebbinghaus*
Angew. Chem. Int. Ed., 55(9):3224-8, 2016.

Press release


Faltung einer RNA-Haarnadel in der dicht gedrängten Zelle

M. Gao#, D. Gnutt#, A. Orban, B. Appel, F. Righetti, R. Winter, F. Narberhaus, S. Müller, S. Ebbinghaus*
Angew. Chem. Int. Ed., 128(9):3279–83, 2016.

Pressemitteilung


Simultaneous measurements of photocurrents and H2O2 evolution from solvent exposed Photosystem 2 complexes

T. Vöpel, E.N. Saw, V. Hartmann, R. Williams, F. Müller, W. Schuhmann, N. Plumeré, M. Nowaczyk, S. Ebbinghaus*, M. Rögner*
Biointerphases, 11, 019001, 2016.


Vom Reagenzglas in die Zelle

D. Gnutt, M. Heyden* and S. Ebbinghaus*
Nachrichten aus der Chemie (Trendbericht Physikalische Chemie), 03/2016.


The macromolecular crowding effect – from in vitro into the cell

D. Gnutt and S. Ebbinghaus*
Biol. Chem., 397(1):37-44, 2016.


Protein stability in crowded environments

M. Senske, S. Ebbinghaus and C. Herrmann*
Book chapter in Biocalorimetry: Foundations and Contemporary Approaches
(Taylor & Francis), 13:241-253, 2016.


Infrared laser triggered release of bioactive compounds from single hard shell microcapsules

T. Vöpel, R. Scholz, L. Davico, M. Groß, S. Büning, S. Kareth, E. Weidner and S. Ebbinghaus*
Chem. Commun., 51, 6913-6916, 2015.

Selected for the Back Cover.


Excluded volume effects in the living cell

D. Gnutt, M. Gao, O. Brylski, M. Heyden and S. Ebbinghaus*
Angew. Chem. Int. Ed., 54(8):2548–51, 2015

Selected as "Hot Paper"
Press release



Effekte des Volumenausschlusses in lebenden Zellen

D. Gnutt, M. Gao, O. Brylski, M. Heyden and S. Ebbinghaus*
Angew. Chem., 127(8): 2578–81, 2015

Ausgezeichnet als "Hot Paper"
Pressemitteilung


Modulation of human IAPP fibrillation: Cosolutes, crowders and chaperones

M. Gao, K. Estel, J. Seeliger, R.P. Friedrich, S. Dogan, E.E. Wanker, R. Winter and S. Ebbinghaus*
Phys. Chem. Chem. Phys., 17, 8338-48, 2015.

Selected for the Back Cover.


Non-invasive chemical assessment of living human spermatozoa

E. Edengeiser, K. Meister, E. Bründermann, S. Büning, S. Ebbinghaus, M. Havenith*
RSC Advances, (5), 10424-10429, 2015


Understanding the ‘native’ solvent – from the test tube into the cell

M. Senske, S. Büning and S. Ebbinghaus*
Bunsenmagazin, (6), 276–281, 2014.


Protein Stabilization by Macromolecular Crowding through Enthalpy rather than Entropy

M. Senske, L. Törk, B. Born, M. Havenith, C. Herrmann and S. Ebbinghaus*
J. Am. Chem. Soc., 136 (25), 9036–9041, 2014.

Press release: “Work environment” affects protein properties


Relaxationskinetik in lebenden Zellen

S. Büning, S. Ebbinghaus*
BIOspektrum, 20(4), 383-385, 2014.


Particle Dynamics Microscopy Using Temperature Jump and Probe Anticorrelation/Correlation Techniques.

M. Gruebele, S. Ebbinghaus, A. Dhar, J.D. McDonald
US patent 8,757,871, 2014


Probing solvation dynamics by THz absorption spectroscopy

B. Born, M. Heyden, S. Ebbinghaus and M. Havenith*
Terahertz Biomedical Science and Technology, CRC Press, 2014


Long-range protein-water dynamics in hyperactive insect antifreeze proteins

K. Meister, S. Ebbinghaus, Y. Xu, J.G. Duman, A.L. DeVries, M. Gruebele, D.M. Leitner and M. Havenith*
Proc. Nat. Acad. Sci. USA, 110(5):1617-1622, 2013.

"How An Insect Version Of Antifreeze Works" Veröffentlichung in Chemical & Engineering News


Functional Importance of Short-Range Binding and Long-Range Solvent Interactions in Helical Antifreeze Peptides

S. Ebbinghaus, K. Meister, M. B. Prigozhin, A. L. DeVries, M. Havenith, J. Dzubiella, and M. Gruebele*
Biophys. J., 103:20-22, 2012.


Protein Stability and Folding Kinetics in the Nucleus and Endoplasmic Reticulum of Eucaryotic Cells

A. Dhar, K. Girdhar, D. Singh, H. Gelman, S. Ebbinghaus, M. Gruebele*
Biophys. J., 101:1-10, 2011.


Protein Folding Landscapes in the Living Cell

S. Ebbinghaus and M. Gruebele*
J. Phys. Chem. Lett., 2:314-319, 2011.


Structure, function, and folding of phosphoglycerate kinase are strongly perturbed by macromolecular crowding

A. Dhar, A. Samiotakis, S. Ebbinghaus, L. Nienhaus, D. Homouz, M. Gruebele, M.S. Cheung*
Proc. Nat. Acad. Sci. USA, 107:17586-17591, 2010.


The diffusion coefficient for PGK folding in eukaryotic cells

A. Dhar#, S. Ebbinghaus#, Z. Shen, T. Mishra, M. Gruebele*
Biophys. J., 99:69-71, 2010.


Antifreeze glycoprotein activity correlates with long-range protein-water dynamics

S. Ebbinghaus, K. Meister, B. Born, A. L. DeVries, M. Gruebele and M. Havenith*
J. Am. Chem. Soc., 132:12210-12211, 2010.


Terahertz Spectroscopy as a Tool to Study Hydration Dynamics

M. Heyden, S. Ebbinghaus, M. Havenith*
Encyclopedia of Analytical Chemistry, Analytical Chemistry, eds R.A. Meyers, John Wiley: Chichester, 2010.


Protein folding stability and dynamics imaged in a living cell

S. Ebbinghaus, A. Dhar, J.D. McDonald and M. Gruebele*
Nature Methods, 7:319-323, 2010.


The terahertz dance of water with the proteins: the effect of protein flexibility on the dynamical hydration shell of ubiquitin

B. Born, S.J. Kim, S. Ebbinghaus, M. Gruebele, M. Havenith*
Faraday Discuss., 141:161-173, 2009.


Protein sequence- and pH-dependent hydration probed by Terahertz spectroscopy

S. Ebbinghaus, S.J. Kim, M. Heyden, X. Yu, M. Gruebele, D. Leitner and M. Havenith*
J. Am. Chem. Soc., 130:2374-2375, 2008.


An extended dynamical solvation shell around proteins

S. Ebbinghaus, S.J. Kim, M. Heyden, X. Yu, U. Heugen, M. Gruebele, D. Leitner and
M. Havenith*
Proc. Nat. Acad. Sci. USA, 104:20749-20752, 2007.


Terahertz time-domain spectroscopy as a new tool for the characterization of dust forming plasmas

S. Ebbinghaus, K. Schröck, J.C. Schauer, E. Bründermann, M. Heyden, G. Schwaab,
M. Böke, J. Winter, M. Tani and M. Havenith*
Plasma Sources Sci.Technol., 15:72-77, 2006.


Terahertz Imaging Applications in Spectroscopy of Biomolecules

E. Bründermann, U. Heugen, R. Schiwon, B. Born, G.W. Schwaab, S. Ebbinghaus, K.
Schröck, D.R. Chamberlin, E.E. Haller and M. Havenith*
Microwave Symposium Digest, IEEE MTT-SInternational:625-628, 2005.


High resolution spectroscopy of the ν3 band of DCOOD

F. Madeja, A. Hecker, S. Ebbinghaus and M. Havenith*
Spectrochimica Acta Part A, 59:1773, 2003.


High resolution spectroscopy of the ν3 band of the van der Waals complex Ar-DCOOH

F. Madeja, A. Hecker, S. Ebbinghaus and M. Havenith*
Mol. Phys., 101:1511, 2003.