| 2016 |
Bikbaev A, Manahan-Vaughan D.
Metabotropic glutamate receptor, mGlu5, regulates hippocampal synaptic plasticity and is required for tetanisation-triggered changes in theta and gamma oscillations.
Neuropharmacology. 2016 Jul 6. pii: S0028-3908(16)30244-1. doi: 10.1016/j.neuropharm.2016.06.004. [Epub ahead of print] |
Manahan-Vaughan D, Wolf OT, Güntürkün O.
Editorial: Extinction Learning from a Mechanistic and Systems Perspective.
Front Behav Neurosci. 2016 Jun 13;10:115. doi: 10.3389/fnbeh.2016.00115. eCollection 2016. No abstract available. |
Hagena H, Manahan-Vaughan D.
The serotonergic 5-HT4 receptor: A unique modulator of hippocampal synaptic information processing and cognition.
Neurobiol Learn Mem. 2016 Jun 15. pii: S1074-7427(16)30089-2. doi: 10.1016/j.nlm.2016.06.014. [Epub ahead of print] |
Buschler A, Manahan-Vaughan D.
Metabotropic glutamate receptor, mGlu5, mediates enhancements of hippocampal long-term potentiation after environmental enrichment in young and old mice.
Neuropharmacology. 2016 Jun 4. pii: S0028-3908(16)30243-X. doi: 10.1016/j.neuropharm.2016.06.003. [Epub ahead of print] |
Blank T, Detje CN, Spieß A, Hagemeyer N, Brendecke SM, Wolfart J, Staszewski O, Zöller T, Papageorgiou I, Schneider J, Paricio-Montesinos R, Eisel UL, Manahan-Vaughan D, Jansen S, Lienenklaus S, Lu B, Imai Y, Müller M, Goelz SE, Baker DP, Schwaninger M, Kann O, Heikenwalder M, Kalinke U, Prinz M.
Brain Endothelial- and Epithelial-Specific Interferon Receptor Chain 1 Drives Virus-Induced Sickness Behavior and Cognitive Impairment.
Immunity. 2016 Apr 19;44(4):901-12. doi: 10.1016/j.immuni.2016.04.005. |
Dietz B, Manahan-Vaughan D.
Hippocampal long-term depression is facilitated by the acquisition and updating of memory of spatial auditory content and requires mGlu5 activation.
Neuropharmacology. 2016 Apr 4. pii: S0028-3908(16)30061-2. doi: 10.1016/j.neuropharm.2016.02.026. [Epub ahead of print] |
André MA, Manahan-Vaughan D.
Involvement of Dopamine D1/D5 and D2 Receptors in Context-Dependent Extinction Learning and Memory Reinstatement.
Front Behav Neurosci. 2016 Jan 21;9:372. doi: 10.3389/fnbeh.2015.00372. eCollection 2015. |
Hagena H, Hansen N, Manahan-Vaughan D.
β-Adrenergic Control of Hippocampal Function: Subserving the Choreography of Synaptic Information Storage and Memory.
Cereb Cortex. 2016 Apr;26(4):1349-64. doi: 10.1093/cercor/bhv330. Epub 2016 Jan 24. |
Twarkowski H, Hagena H, Manahan-Vaughan D.
The 5-hydroxytryptamine4 receptor enables differentiation of informational content and encoding in the hippocampus.
Hippocampus. 2016 Jul;26(7):875-91. doi: 10.1002/hipo.22569. Epub 2016 Feb 17. |
Aarse J, Herlitze S, Manahan-Vaughan D.
The requirement of BDNF for hippocampal synaptic plasticity is experience-dependent.
Hippocampus. 2016 Jun;26(6):739-51. doi: 10.1002/hipo.22555. Epub 2016 Jan 19. |
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| 2015 |
André MA, Wolf OT, Manahan-Vaughan D.
Beta-adrenergic receptors support attention to extinction learning that occurs in the absence, but not the presence, of a context change.
Front Behav Neurosci. 2015 May 27;9:125. doi: 10.3389/fnbeh.2015.00125. eCollection 2015. |
Grüter T, Wiescholleck V, Dubovyk V, Aliane V, Manahan-Vaughan D.
Altered neuronal excitability underlies impaired hippocampal function in an animal model of psychosis.
Front Behav Neurosci. 2015 May 20;9:117. doi: 10.3389/fnbeh.2015.00117. eCollection 2015. |
Kalweit AN, Yang H, Colitti-Klausnitzer J, Fülöp L, Bozsó Z, Penke B, Manahan-Vaughan D.
Acute intracerebral treatment with amyloid-beta (1-42) alters the profile of neuronal oscillations that accompany LTP induction and results in impaired LTP in freely behaving rats.
Front Behav Neurosci. 2015 May 6;9:103. doi: 10.3389/fnbeh.2015.00103. eCollection 2015. |
Novkovic T, Heumann R, Manahan-Vaughan D.
Ras does not contribute to the facilitation of hippocampal synaptic plasticity enabled by environmental enrichment.
Neuroscience. 2015 Nov 19;309:214-23. doi: 10.1016/j.neuroscience.2015.04.052. Epub 2015 Apr 29. |
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Hagena H, Manahan-Vaughan D.
mGlu5 Acts As a Switch for Opposing Forms of Synaptic Plasticity at Mossy Fiber-CA3 and Commissural Associational-CA3 Synapses.
J Neurosci. 2015 Mar 25;35(12):4999-5006. doi: 10.1523/JNEUROSCI.3417-14.2015.
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Novkovic T, Shchyglo O, Gold R, Manahan-Vaughan D.
Hippocampal function is compromised in an animal model of multiple sclerosis.
Neuroscience. 2015 Mar 17. pii: S0306-4522(15)00223-7. doi: 10.1016/j.neuroscience.2015.03.008. [Epub ahead of print]
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Aksoy-Aksel A, Manahan-Vaughan D.
Synaptic strength at the temporoammonic input to the hippocampal CA1 region in vivo is regulated by NMDA receptors, metabotropic glutamate receptors and voltage-gated calcium channels.
Neuroscience. 2015 Mar 17. pii: S0306-4522(15)00236-5. doi: 10.1016/j.neuroscience.2015.03.014. [Epub ahead of print]
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Hansen N, Manahan-Vaughan D.
Hippocampal long-term potentiation that is elicited by perforant path stimulation or that occurs in conjunction with spatial learning is tightly controlled by beta-adrenoreceptors and the locus coeruleus.
Hippocampus. 2015 Feb 27. doi: 10.1002/hipo.22436. [Epub ahead of print]
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| 2014 |
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Barmashenko G, Buttgereit J, Herring N, Bader M, Ozcelik C, Manahan-Vaughan D, Braunewell KH.
Regulation of hippocampal synaptic plasticity thresholds and changes in exploratory and learning behavior in dominant negative NPR-B mutant rats.
Front Mol Neurosci. 2014 Dec 1;7:95. doi: 10.3389/fnmol.2014.00095. eCollection 2014.
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André MA, Güntürkün O, Manahan-Vaughan D.
The metabotropic glutamate receptor, mGlu5, is required for extinction learning that occurs in the absence of a context change.
Hippocampus. 2015 Feb;25(2):149-58. doi: 10.1002/hipo.22359. Epub 2014 Sep 30
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Kruse W, Krause M, Aarse J, Mark MD, Manahan-Vaughan D, Herlitze S.
Optogenetic modulation and multi-electrode analysis of cerebellar networks in vivo.
PLoS One. 2014 Aug 21;9(8):e105589. doi: 10.1371/journal.pone.0105589. eCollection 2014.
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Novkovic T, Mittmann T, Manahan-Vaughan D.
BDNF contributes to the facilitation of hippocampal synaptic plasticity and learning enabled by environmental enrichment.
Hippocampus. 2015 Jan;25(1):1-15. doi: 10.1002/hipo.22342. Epub 2014 Aug 28.
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Wiescholleck V, Manahan-Vaughan D.
Antagonism of D1/D5 receptors prevents long-term depression (LTD) and learning-facilitated LTD at the perforant path-dentate gyrus synapse in freely behaving rats.
Hippocampus. 2014 Dec;24(12):1615-22. doi: 10.1002/hipo.22340. Epub 2014 Aug 27.
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Zhang S, Schönfeld F, Wiskott L, Manahan-Vaughan D.
Spatial representations of place cells in darkness are supported by path integration and border information.
Front Behav Neurosci. 2014 Jun 24;8:222. doi: 10.3389/fnbeh.2014.00222. eCollection 2014.
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Zhang S, Manahan-Vaughan D.
Place field stability requires the metabotropic glutamate receptor, mGlu5.
Hippocampus. 2014 Nov;24(11):1330-40. doi: 10.1002/hipo.22314. Epub 2014 Jun 25.
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Goh JJ, Manahan-Vaughan D.
Role of inhibitory autophosphorylation of calcium/calmodulin-dependent kinase II (αCAMKII) in persistent (>24h) hippocampal LTP and in LTD facilitated by novel object-place learning and recognition in mice.
Behav Brain Res. 2015 May 15;285:79-88. doi: 10.1016/j.bbr.2014.01.022. Epub 2014 Jan 27.
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Hansen N, Manahan-Vaughan D.
Locus Coeruleus Stimulation Facilitates Long-Term Depression in the Dentate Gyrus That Requires Activation of β-Adrenergic Receptors.
Cereb Cortex. 2014 Jan 23. [Epub ahead of print]
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2013
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Blot K, Kimura SI, Bai J, Kemp A, Manahan-Vaughan D, Giros B, Tzavara E, Otani S.
Modulation of Hippocampus-Prefrontal Cortex Synaptic Transmission and Disruption of Executive Cognitive Functions by MK-801.
Cereb Cortex. 2013 Dec 4. [Epub ahead of print]
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Kenney J, Manahan-Vaughan D.
Learning-facilitated synaptic plasticity occurs in the intermediate hippocampus in association with spatial learning.
Front Synaptic Neurosci. 2013 Oct 29;5:10. doi: 10.3389/fnsyn.2013.00010. eCollection 2013.
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Wiescholleck V, Emma André MA, Manahan-Vaughan D.
Early age-dependent impairments of context-dependent extinction learning, object recognition, and object-place learning occur in rats.
Hippocampus. 2014 Mar;24(3):270-9. doi: 10.1002/hipo.22220. Epub 2013 Nov 12.
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Zhang S, Manahan-Vaughan D.
Spatial olfactory learning contributes to place field formation in the hippocampus.
Cereb Cortex. 2015 Feb;25(2):423-32. doi: 10.1093/cercor/bht239. Epub 2013 Sep 5.
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Aksoy-Aksel A, Manahan-Vaughan D.
The temporoammonic input to the hippocampal CA1 region displays distinctly different synaptic plasticity compared to the Schaffer collateral input in vivo: significance for synaptic information processing.
Front Synaptic Neurosci. 2013 Aug 23;5:5. doi: 10.3389/fnsyn.2013.00005. eCollection 2013.
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Goh JJ, Manahan-Vaughan D.
Hippocampal long-term depression in freely behaving mice requires the activation of beta-adrenergic receptors.
Hippocampus. 2013 Dec;23(12):1299-308. doi: 10.1002/hipo.22168. Epub 2013 Sep 2
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André MA, Manahan-Vaughan D.
Spatial olfactory learning facilitates long-term depression in the hippocampus.
Hippocampus. 2013 Jul 19;23(10):963-8. doi: 10.1002/hipo.22158. |
Kemp A, Tischmeyer W, Manahan-Vaughan D.
Learning-facilitated long-term depression requires activation of the immediate early gene, c-fos, and is transcription dependent.
Behav Brain Res. 2013 Apr 30. doi:pii: S0166-4328(13)00244-1. 10.1016/j.bbr.2013.04.036. [Epub ahead of print] |
Wiescholleck V, Manahan-Vaughan D.
Persistent deficits in hippocampal synaptic plasticity accompany losses of hippocampus-dependent memory in a rodent model of psychosis.
Front Integr Neurosci. 2013;7:12. doi: 10.3389/fnint.2013.00012. Epub 2013 Mar 15. |
Kenney J, Manahan-Vaughan D.
NMDA receptor-dependent synaptic plasticity in dorsal and intermediate hippocampus exhibits distinct frequency-dependent profiles.
Neuropharmacology. 2013 Mar 13. doi:pii: S0028-3908(13)00074-9. 10.1016/j.neuropharm.2013.02.017. [Epub ahead of print] |
Hagena H, Manahan-Vaughan D.
Differentiation in the protein synthesis-dependency of persistent synaptic plasticity in mossy fiber and associational/commissural CA3 synapses in vivo.
Front Integr Neurosci. 2013;7:10. doi: 10.3389/fnint.2013.00010. Epub 2013 Mar 1. |
Wiescholleck V, Manahan-Vaughan D.
Long-lasting changes in hippocampal synaptic plasticity and cognition in an animal model of NMDA receptor dysfunction in psychosis.
Neuropharmacology. 2013 Jan 31. doi:pii: S0028-3908(13)00005-1. 10.1016/j.neuropharm.2013.01.001. [Epub ahead of print] |
Goh JJ, Manahan-Vaughan D.
Synaptic depression in the CA1 region of freely behaving mice is highly dependent on afferent stimulation parameters.
Front Integr Neurosci. 2013;7:1. doi: 10.3389/fnint.2013.00001. Epub 2013 Jan 25. |
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2012
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Prochnow N, Abdulazim A, Kurtenbach S, Wildförster V, Dvoriantchikova G, Hanske J, Petrasch-Parwez E, Shestopalov VI, Dermietzel R, Manahan-Vaughan D, Zoidl G.
Pannexin1 stabilizes synaptic plasticity and is needed for learning.
PLoS One. 2012;7(12):e51767. doi: 10.1371/journal.pone.0051767. Epub 2012 Dec 20. Erratum in: PLoS One. 2013;8(1). doi:10.1371/annotation/d0972416-5fef-4f89-9c09-cb4cb0c6295d |
Buschler A, Manahan-Vaughan D.
Brief environmental enrichment elicits metaplasticity of hippocampal synaptic potentiation in vivo.
Front Behav Neurosci. 2012;6:85. doi: 10.3389/fnbeh.2012.00085. Epub 2012 Dec 14. |
Hansen N, Manahan-Vaughan D.
Dopamine D1/D5 Receptors Mediate Informational Saliency that Promotes Persistent Hippocampal Long-Term Plasticity.
Cereb Cortex. 2012 Nov 25. [Epub ahead of print] |
Goh JJ, Manahan-Vaughan D.
Endogenous hippocampal LTD that is enabled by spatial object recognition requires activation of NMDA receptors and the metabotropic glutamate receptor, mGlu5.
Hippocampus. 2013 Feb;23(2):129-38. doi: 10.1002/hipo.22072. Epub 2012 Sep 21. |
Wiescholleck V, Manahan-Vaughan D.
PDE4 inhibition enhances hippocampal synaptic plasticity in vivo and rescues MK801-induced impairment of long-term potentiation and object recognition memory in an animal model of psychosis.
Transl Psychiatry. 2012 Mar 13;2:e89. doi: 10.1038/tp.2012.17. |
Mukherjee S, Manahan-Vaughan D.
Role of metabotropic glutamate receptors in persistent forms of hippocampal plasticity and learning.
Neuropharmacology. 2013 Mar;66:65-81. doi: 10.1016/j.neuropharm.2012.06.005. Epub 2012 Jun 26. |
Hagena H, Manahan-Vaughan D.
Learning-facilitated long-term depression and long-term potentiation at mossy fiber-CA3 synapses requires activation of β-adrenergic receptors.
Front Integr Neurosci. 2012;6:23. doi: 10.3389/fnint.2012.00023. Epub 2012 May 23. |
Goh JJ, Manahan-Vaughan D.
Spatial Object Recognition Enables Endogenous LTD that Curtails LTP in the Mouse Hippocampus.
Cereb Cortex. 2012 Apr 17. [Epub ahead of print] |
Seebohm G, Neumann S, Theiss C, Novkovic T, Hill EV, Tavaré JM, Lang F, Hollmann M, Manahan-Vaughan D, Strutz-Seebohm N.
Identification of a novel signaling pathway and its relevance for GluA1 recycling.
PLoS One. 2012;7(3):e33889. doi: 10.1371/journal.pone.0033889. Epub 2012 Mar 21. |
Lemon N, Manahan-Vaughan D.
Dopamine D1/D5 receptors contribute to de novo hippocampal LTD mediated by novel spatial exploration or locus coeruleus activity.
Cereb Cortex. 2012 Sep;22(9):2131-8. doi: 10.1093/cercor/bhr297. Epub 2011 Oct 29. |
Kemp A, Manahan-Vaughan D.
Passive spatial perception facilitates the expression of persistent hippocampal long-term depression.
Cereb Cortex. 2012 Jul;22(7):1614-21. doi: 10.1093/cercor/bhr233. Epub 2011 Sep 13. |
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2011
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Hagena H, Manahan-Vaughan D.
Learning-facilitated synaptic plasticity at CA3 mossy fiber and commissural-associational synapses reveals different roles in information processing.
Cereb Cortex. 2011 Nov;21(11):2442-9. doi: 10.1093/cercor/bhq271. Epub 2011 Apr 14. |
Yang H, Courtney MJ, Martinsson P, Manahan-Vaughan D.
Hippocampal long-term depression is enhanced, depotentiation is inhibited and long-term potentiation is unaffected by the application of a selective c-Jun N-terminal kinase inhibitor to freely behaving rats.
Eur J Neurosci. 2011 May;33(9):1647-55. doi: 10.1111/j.1460-9568.2011.07661.x. Epub 2011 Mar 31. |
Manahan-Vaughan D, Schwegler H.
Strain-dependent variations in spatial learning and in hippocampal synaptic plasticity in the dentate gyrus of freely behaving rats.
Front Behav Neurosci. 2011 Mar 7;5:7. doi: 10.3389/fnbeh.2011.00007. |
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Popkirov SG, Manahan-Vaughan D.
Involvement of the metabotropic glutamate receptor mGluR5 in NMDA receptor-dependent, learning-facilitated long-term depression in CA1 synapses.
Cereb Cortex. 2011 Mar;21(3):501-9. doi: 10.1093/cercor/bhq093. Epub 2010 Jun 4.
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2010
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Manahan-Vaughan D (2010)
MicroRNAs contribute to LTP in the hippocampus in vivo (Commentary on Wibrand et al.).
Eur J Neurosci. 31(4):634-5 |
Goh JJ, Manahan-Vaughan D.
Hippocampal long-term depression in freely behaving mice requires the activation of beta-adrenergic receptors.
Hippocampus. 2013 Dec;23(12):1299-308. doi: 10.1002/hipo.22168. Epub 2013 Sep 2 |
Hagena H, Manahan-Vaughan D (2010)
Frequency facilitation at mossy fiber-CA3 synapses of freely behaving rats contributes to the induction of persistent LTD via an adenosine-A1 receptor-regulated mechanism.
Cereb Cortex 20(5):1121-30. |
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2009
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Tsanov M, Manahan-Vaughan D (2009)
Visual cortex plasticity evokes excitatory alterations in the hippocampus.
Front Integr Neurosci. 3:32. |
Tsanov M, Manahan-Vaughan D (2009)
Synaptic plasticity in the adult visual cortex is regulated by the metabotropic glutamate receptor, mGLUR5.
Exp Brain Res. 2009 Aug 12. [Epub ahead of print] |
Lemon N, Abidin-Aydin S, Funke K, Manahan-Vaughan D (2009)
Locus coeruleus activation facilitates memory encoding and induces hippocampal LTD that depend on beta-adrenergic receptor activation.
Cerebral Cortex 19(12):2827-37. |
Tsanov M, Manahan-Vaughan D (2009)
Long-term plasticity is proportional to theta-activity.
PLoS One, 4(6):e5850. |
Stricker S, Manahan-Vaughan D. (2009)
Regulation of long-term depression by increases in [guanosine 3',5'-cyclic monophosphate] in the hippocampal CA1 region of freely behaving rats.
Neuroscience. 158(1): 159-66. |
Davanger S, Manahan-Vaughan D, Mulle C, Storm-Mathisen J, Ottersen OP. (2009)
Protein trafficking, targeting, and interaction at the glutamate synapse.
Neuroscience. 158(1): 1-3. |
Altinbilek B, Manahan-Vaughan D. (2009)
A specific role for group II metabotropic glutamate receptors in hippocampal long-term depression and spatial memory.
Neuroscience. 158(1):149-158. |
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| 2008 |
Manahan-Vaughan D, Wildförster V, Thomsen C. (2008)
Rescue of hippocampal LTP and learning deficits in a rat model of psychosis by inhibition of glycine transporter-1 (GlyT1).
Eur J Neurosci. 28(7):1342-50. |
Bikbaev A, Manahan-Vaughan D. (2008)
Relationship of hippocampal theta and gamma oscillations to potentiation of synaptic transmission.
Front Neurosci. 2:56-63. |
Tsanov M, Manahan-Vaughan D. (2008)
Synaptic plasticity from visual cortex to hippocampus: systems integration in spatial information processing.
Neuroscientist. 14(6):584-97. |
Bikbaev A, Neyman S, Ngomba RT, Conn J, Nicoletti F, Manahan-Vaughan D. (2008)
MGluR5 mediates the interaction between late-LTP, network activity, and learning.
PLoS ONE. 3(5):e2155. |
Klausnitzer J, Manahan-Vaughan D. (2008)
Frequency facilitation at mossy fiber-CA3 synapses of freely behaving rats is regulated by adenosine A1 receptors.
J Neurosci. 28(18):4836-40 |
Neyman S, Manahan-Vaughan D. (2008)
Metabotropic glutamate receptor 1 (mGluR1) and 5 (mGluR5) regulate late phases of LTP and LTD in the hippocampal CA1 region in vitro.
Eur J Neurosci. 27(6):1345-52. |
Kemp A, Manahan-Vaughan D. (2008)
The hippocampal CA1 region and dentate gyrus differentiate between environmental and spatial feature encoding through long-term depression.
Cereb Cortex. 18(4):968-77. Epub 2007 Aug 16. |
Kulla A, Manahan-Vaughan D. (2008)
Modulation by group 1 metabotropic glutamate receptors of depotentiation in the dentate gyrus of freely moving rats.
Hippocampus. 18(1):48-54. |
Manahan-Vaughan D, von Haebler D, Winter C, Juckel G, Heinemann U. (2008)
A single application of MK801 causes symptoms of acute psychosis, deficits in spatial memory, and impairment of synaptic plasticity in rats.
Hippocampus. 18(2):125-34. |
Kemp A, Manahan-Vaughan D. (2008)
Beta-adrenoreceptors comprise a critical element in learning-facilitated long-term plasticity.
Cereb Cortex. 18(6):1326-34. |
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| 2007 |
Bikbaev A, Manahan-Vaughan D. (2007)
Hippocampal Network Activity is Transiently Altered by Induction of Long-Term Potentiation in the Dentate Gyrus of Freely Behaving Rats.
Front Behav Neurosci. 2007;1:7 |
Wöhrl R, Eisenach S, Manahan-Vaughan D, Heinemann U, von Haebler D. (2007)
Acute and long-term effects of MK-801 on direct cortical input evoked homosynaptic and heterosynaptic plasticity in the CA1 region of the female rat.
Eur J Neurosci. 26(10):2873-83. |
Altinbilek B, Manahan-Vaughan D. (2007)
Antagonism of group III metabotropic glutamate receptors results in impairment of LTD but not LTP in the hippocampal CA1 region, and prevents long-term spatial memory.
Eur J Neurosci. 26(5):1166-72. |
Tsanov M, Manahan-Vaughan D. (2007)
Intrinsic, light-independent and visual activity-dependent mechanisms cooperate in the shaping of the field response in rat visual cortex.
J Neurosci. 27(31):8422-9. |
Tsanov M, Manahan-Vaughan D. (2007)
The adult visual cortex expresses dynamic synaptic plasticity that is driven by the light/dark cycle.
J Neurosci. 27(31):8414-21. |
Naie K, Tsanov M, Manahan-Vaughan D. (2007)
Group I metabotropic glutamate receptors enable two distinct forms of long-term depression in the rat dentate gyrus in vivo.
Eur J Neurosci. 25(11):3264-75. |
Kemp A, Manahan-Vaughan D (2007)
Hippocampal long-term depression: master or minion of declarative memory processes.
Trends Neurosci. 30(3):111-8. |
Poschel B, Manahan-Vaughan D. (2007)
Persistent (>24h) long-term depression in the dentate gyrus of freely moving rats is not dependent on activation of NMDA receptors, L-type voltage-gated calcium channels or protein synthesis.
Neuropharmacology. 52:46-54 |
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2006
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Lemon N, Manahan-Vaughan D. (2006)
Dopamine D1/D5 receptors gate the acquisition of novel information through hippocampal long-term potentiation and long-term depression.
J Neurosci. 26(29):7723-7729. |
Naie K, Gundimi S, Siegmund H, Heinemann U, Manahan-Vaughan D. (2006)
Group III metabotropic glutamate receptor-mediated, chemically induced long-term depression differentially affects cell viability in the hippocampus.
Eur J Pharmacol. 535(1-3):104-13. |
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2005
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Zhang L, Kirschstein T, Sommersberg B, Merkens M, Manahan-Vaughan D, Elgersma Y, Beck H. (2005)
Hippocampal synaptic metaplasticity requires inhibitory autophosphorylation of Ca2+/calmodulin-dependent kinase II.
J Neurosci. 25:7697-707 |
Poschel B, Manahan-Vaughan D. (2005)
Group II mGluR-induced long term depression in the dentate gyrus in vivo is NMDA receptor-independent and does not require protein synthesis.
Neuropharmacology. 49 Suppl 1:1-12. |
Naie K, Manahan-Vaughan D. (2005)
Investigations of the protein synthesis dependency of mGluR-induced long-term depression in the dentate gyrus of freely moving rats.
Neuropharmacology. 49 Suppl 1:35-44. |
Manahan-Vaughan D, Braunewell KH. (2005)
The metabotropic glutamate receptor, mGluR5, is a key determinant of good and bad spatial learning performance and hippocampal synaptic plasticity.
Cereb Cortex. 15:1703-13. |
Naie K, Manahan-Vaughan D. (2005)
Pharmacological antagonism of metabotropic glutamate receptor 1 regulates long-term potentiation and spatial reference memory in the dentate gyrus of freely moving rats via N-methyl-D-aspartate and metabotropic glutamate receptor-dependent mechanisms.
Eur J Neurosci. 21:411-21. |
Poschel B, Wroblewska B, Heinemann U, Manahan-Vaughan D. (2005)
The metabotropic glutamate receptor mGluR3 is critically required for hippocampal long-term depression and modulates long-term potentiation in the dentate gyrus of freely moving rats.
Cereb Cortex. 15:1414-23. |
Kemp A, Manahan-Vaughan D. (2005)
The 5-hydroxytryptamine4 receptor exhibits frequency-dependent properties in synaptic plasticity and behavioural metaplasticity in the hippocampal CA1 region in vivo.
Cereb Cortex. 15:1037-43. |
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2004
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Brackmann M, Zhao C, Kuhl D, Manahan-Vaughan D, Braunewell KH. (2004)
MGluRs regulate the expression of neuronal calcium sensor proteins NCS-1 and VILIP-1 and the immediate early gene arg3.1/arc in the hippocampus in vivo.
Biochem Biophys Res Commun. 322:1073-9. |
Kemp A, Manahan-Vaughan D. (2004)
Hippocampal long-term depression and long-term potentiation encode different aspects of novelty acquisition.
Proc Natl Acad Sci U S A. 101:8192-7. |
Klausnitzer J, Kulla A, Manahan-Vaughan D. (2004)
Role of the group III metabotropic glutamate receptor in LTP, depotentiation and LTD in dentate gyrus of freely moving rats.
Neuropharmacology. 46(2):160-70. |
Solger J, Wozny C, Manahan-Vaughan D, Behr J. (2004)
Distinct mechanisms of bidirectional activity-dependent synaptic plasticity in superficial and deep layers of rat entorhinal cortex.
Eur J Neurosci. 19:2003-7. |
Blandini F, Braunewell KH, Manahan-Vaughan D, Orzi F, Sarti P. (2004)
Neurodegeneration and energy metabolism.
Cell Death Differ. 11:479-84. |
Naie K, Manahan-Vaughan D. (2004)
Regulation by metabotropic glutamate receptor 5 of LTP in the dentate gyrus of freely moving rats: relevance for learning and memory formation.
Cereb Cortex. 14:189-98. |
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2003
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Braunewell KH, Brackmann M, Manahan-Vaughan D. (2003)
Group I mGlu receptors regulate the expression of the neuronal calcium sensor protein VILIP-1 in vitro and in vivo: implications for mGlu receptor-dependent hippocampal plasticity?
Neuropharmacology. 44:707-15. |
Manahan-Vaughan D, Ngomba RT, Storto M, Kulla A, Catania MV, Chiechio S, Rampello L, Passarelli F, Capece A, Reymann KG, Nicoletti F. (2003)
An increased expression of the mGlu5 receptor protein following LTP induction at the perforant path-dentate gyrus synapse in freely moving rats.
Neuropharmacology. 44(1):17-25. |
Manahan-Vaughan D, Kulla A. (2003)
Regulation of depotentiation and long-term potentiation in the dentate gyrus of freely moving rats by dopamine D2-like receptors.
Cereb Cortex. 13(2):123-35. |
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2002
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Kulla A, Manahan-Vaughan D. (2002)
Modulation by serotonin 5-HT(4) receptors of long-term potentiation and depotentiation in the dentate gyrus of freely moving rats.
Cereb Cortex. 12(2):150-62. |
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2001
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Braunewell KH, Manahan-Vaughan D. (2001)
Long-term depression: a cellular basis for learning?
Rev Neurosci. 12:121-40. |
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2000
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Manahan-Vaughan, D., Kulla, A. and Frey J.U. (2000)
Requirement of translation but not transcription for the maintenance of long-term depression in the CA1 region of freely moving rats.
J. Neurosci. 20: 8572-8576. |
Manahan-Vaughan, D. (2000)
Long-term depression in freely moving rats is dependent upon strain variation, induction protocol and behavioral state.
Cerebral Cortex 10: 482-487. |
Kulla, A. and Manahan-Vaughan, D (2000)
Dopamine D1 receptors modulate depotentiation in the dentate gyrus of freely moving rats.
Cerebral Cortex 10: 614-620. |
Manahan-Vaughan, D. (2000)
Group III metabotropic glutamate receptors modulate long-term depression in the hippocampal CA1 region of freely moving rats.
Neuropharmacology39: 1952-1958. |
Spilker C, K Richter, Smalla KH, Manahan-Vaughan D, Gundelfinger ED, Braunewell KH (2000)
The neuronal ef-hand calcium-binding protein visinin-like protein-3 is expressed in cerebellar purkinje cells and shows a calcium-dependent membrane association.
Neuroscience 96: 121 -129 |
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1999
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Manahan-Vaughan, D. and Braunewell KH. (1999)
Novelty acquisition is associated with induction of hippocampal long-term depression.
Proc. Natl. Acad. Sci. USA 96: 8739-8744. |
Manahan-Vaughan, D., Herrero I., Reymann, K.G. and Sanchez-Prieto, J. (1999)
Characterisation of pre- and post-synaptic modulation of LTP by group 1 metabotropic glutamate receptors.
Neuroscience 94: 71-82. |
Kulla, A., Reymann K.G. and Manahan-Vaughan, D (1999)
Involvement of group 2 metabotropic glutamate receptors in hippocampal depotentiation in freely moving rats.
Eur. J. Neurosci. 11: 3864-72. |
Balschun, D., Manahan-Vaughan, D., Wagner, T., Behnisch, T., Reymann, K. G., Wetzel, W. (1999)
A Specific Role for Group I mGluRs in Hippocampal LTP and Hippocampus-Dependent Spatial Learning. Learn.
Mem. 6: 138-152 |
Manahan-Vaughan, D., Behnisch, T. and Reymann, K.G. (1999)
ACPD-mediated slow-onset potentiation in the hippocampus in vivo is associated with cell death.
Neuropharmacology 38: 487-494. |
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1998
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Manahan-Vaughan, D., (1998)
Priming of group 2 metabotropic glutamate receptors facilitates induction of long-term depression in the dentate gyrus of freely moving rats.
Neuropharmacology 37: 1459-1464. |
Nakic, M., Manahan-Vaughan, D Reymann, K.G. and Schachner, M. (1998)
Long-term potentiation in vivo increases rat hippocampal Tenascin-C expression in vivo
J. Neurobiol. 37: 393-404. |
Manahan-Vaughan, D., Braunewell K.H. and Reymann, K.G. (1998)
Subtype-specific involvement of metabotropic glutamate receptors in two forms of long-term potentiation in the dentate gyrus of freely moving rats.
Neuroscience 86, 709-721. |
Manahan-Vaughan, D, Behnisch, T., Behnisch, G., Vieweg, S. and Reymann, K.G. (1998)
Semi-automated analysis of live/dead neurones in digitised colour images from rat hippocampal thin slices.
J. Neurosci. Meth. 82, 85-95 |
Manahan-Vaughan, D., Reymann, K.G. and Brown, R.E. (1998)
In vivo electrophysiological investigations into the role of histamine in the dentate gyrus of the rat.
Neuroscience 84, 783-790. |
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1997
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Manahan-Vaughan, D., (1997)
Group 1 and 2 metabotropic glutamate receptors play differential roles in hippocampal long-term depression and long-term potentiation in freely moving rats.
J. Neuroscience 17, 3293-3302. |
Manahan-Vaughan, D., and Reymann, K.G. (1997)
Group 1 metabotropic glutamate receptors contribute to slow-onset potentiation in the rat CA1 region in vivo:
Neuropharmacology 36, 1533-1538 |
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1996
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Manahan-Vaughan, D., and Reymann, K.G. (1996)
Metabotropic glutamate receptor subtype agonists facilitate LTP within a distinct time window in the dentate gyrus in vivo.
Neuroscience 74, 723-731. |
Manahan-Vaughan D., Reiser M., Pin J.P., Wilsch V., Reymann K.G and Riedel G. (1996)
Physiological and pharmacological profile of trans-azetidine 2,4-dicarboxylic acid: metabotropic glutamate receptor agonism and effects on long-term potentiation.
Neuroscience 72, 999-1008. |
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1995
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Manahan-Vaughan D, Anwyl R, Rowan MJ. (1995)
The azapirone metabolite 1-(2-pyrimidinyl)piperazine depresses excitatory synaptic transmission in the hippocampus of the alert rat via 5-HT1A receptors.
Eur J Pharmacol. 94(2-3):617-624. |
Manahan-Vaughan D, Reymann KG. (1995)
1S,3R-ACPD dose dependently induces a slow onset potentiation in the dentate gyrus in vivo.
Eur J Pharmacol. 294(2-3):497-503. |
Manahan-Vaughan D, Reymann KG. (1995)
Regional and developmental profile of modulation of hippocampal synaptic transmission and LTP by AP4-sensitive mGluRs in vivo.
Neuropharmacology. 34(8):991-1001. |
Riedel G, Manahan-Vaughan D, Kozikowski AP, Reymann KG. (1995)
Metabotropic glutamate receptor agonist trans-azetidine-2,4-dicarboxylic acid facilitates maintenance of LTP in the dentate gyrus in vivo.
Neuropharmacology. 34(8):1107-9. |
Manahan-Vaughan D, Reymann KG. (1995)
1S,3R-ACPD dose-dependently induces a slow-onset potentiation in the rat hippocampal CA1 region in vivo.
Neuropharmacology. 34(8):1103-1105. |
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1994
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Manahan-Vaughan D, Anwyl R, Rowan MJ. (1994)
5-HT1A receptor-mediated inhibition in the hippocampus of the alert rat--effects of repeated gepirone treatment.
Eur J Pharmacol. 260(2-3):149-155. |
Manahan-Vaughan D, Anwyl R, Rowan MJ. (1994)
Adaptive changes in 5-HT1A receptor-mediated hippocampal inhibition in the alert rat produced by repeated 8-OH-DPAT treatment.
Br J Pharmacol. 112(4):1083-1088. |
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| Book articles: |
| Manahan-Vaughan, D. (2005) Hippocampal long-term depression as a deckarative memory mechanism. In: Synaptic plasticity and transsynaptic signaling. New York: Springer.Ed: PK Stanton et al. |
| Manahan-Vaughan, D. (2001) The role of metabotropic glutamate receptors in hippocampal long-term depression and depotentiation in vivo. In: Excitatory Amino Acids: Ten Years later. IOS Press. Ed: E.A. Cavalheiro et al. |
| Manahan-Vaughan, D and Reymann, K.G. (1998) Metabotropic glutamate receptors and hippocampal synaptic plasticity in vivo. In ‘Metabotropic Glutamate Receptors and Brain Function’, F. Moroni, F. Nicoletti and D.E. Pellegrini-Giampietro,eds. Portland Press, London. p 147-169. |
