2011

Selective Hippocampal Neurodegeneration in Transgenic Mice Expressing Small Amounts of Truncated Aß is Induced by pyro-Glu-Aß Formation.
Alexandru A, Jagla W, Graubner S, Becker A, Bäuscher C, Kohlmann S, Sedlmeier R, Raber K, Cynis H, Rönicke R, Reymann K, Petrasch-Parwez E, Hartlage-Rübsamen M, Waniek A, Rossner S, Schilling A, Osmand A, Demuth H-U, von Hörsten S. J. Neurosci 2011 in press

Olfactory neuron-specific expression of A30P alpha-synuclein exacerbates dopamine deficiency and hyperactivity in a novel conditional model of early Parkinson's disease stages.
Nuber  S, Petrasch-Parwez E, Arias-Carrión O, Koch L, Kohl Z,  Schneider J, Calaminus C, Dermietzel R, Samarina A,  Boy J, Huu P. Nguyena HP, Teismann P, Velavan TP, Philipp J. Kahle PJ, von Hörsten S, Fendt  M,  Krüger R Riess O
Neurobiology of Disease, online 05 july 2011
Neuroanatomical correlates of suicide in psychosis: the possible role of von Economo neurons.
Brüne M, Schöbel A, Karau R, Faustmann PM, Dermietzel R, Juckel G, Petrasch-Parwez E.
PLoS One. 2011;6(6):e20936. Epub 2011 Jun 22.
 Ccdc66 null mutation causes retinal degeneration and dysfunction.
Gerding WM, Schreiber S, Schulte-Middelmann T, de Castro Marques A, Atorf J, Akkad DA, Dekomien G, Kremers J, Dermietzel R, Gal A, Rülicke T, Ibrahim S, Epplen JT, Petrasch-Parwez E. Hum Mol Genet. 2011 Jun 29. [Epub ahead of print]

Efficacy of fumaric acid esters in the R6/2 and YAC128 models of Huntington's disease.
Ellrichmann G, Petrasch-Parwez E, Lee DH, Reick C, Arning L, Saft C, Gold R, Linker RA. PLoS One. 2011 Jan 31;6(1):e16172

Theta-Burst Transcranial Magnetic Stimulation Alters Cortical Inhibition.
Benali A, Trippe J, Weiler E, Mix A, Petrasch-Parwez E, Girzalsky W, Eysel UT, Erdmann R, Funke K. J Neurosci. 2011 Jan 26;31(4):1193-1203.PMID: 21273404

Signal transducer and activator of transcription 3-mediated regulation of miR-199a-5p links cardiomyocyte and endothelial cell function in the heart: a key role for ubiquitin-conjugating enzymes.
Haghikia A, Missol-Kolka E, Tsikas D, Venturini L, Brundiers S, Castoldi M, Muckenthaler MU, Eder M, Stapel B, Thum T, Haghikia A, Petrasch-Parwez E, Drexler H, Hilfiker-Kleiner D, Scherr M. Eur Heart J. 2011 May;32(10):1287-97

2010

Generalized progressive retinal atrophy in the Irish Glen of Imaal Terrier is associated with a deletion in the ADAM9 gene.
Kropatsch R, Petrasch-Parwez E, Seelow D, Schlichting A, Gerding WM, Akkad DA, Epplen JT, Dekomien G. Mol Cell Probes. 2010 Dec;24(6):357-63

Variation in the COL29A1 gene in German patients with atopic dermatitis, asthma and chronic obstructive pulmonary disease.
Harazin M, Parwez Q, Petrasch-Parwez E, Epplen JT, Arinir U, Hoffjan S, Stemmler S. J Dermatol. 2010 Aug;37(8):740-2

First appraisal of brain pathology owing to A30P mutant alpha-synuclein. Seidel K, Schöls L, Nuber S, Petrasch-Parwez E, Gierga K, Wszolek Z, Dickson D, Gai WP, Bornemann A, Riess O, Rami A, Den Dunnen WF, Deller T, Rüb U, Krüger R. Ann Neurol. 2010 May;67(5):684-9

Von Economo neuron density in the anterior cingulate cortex is reduced in early onset schizophrenia.
Brüne M, Schöbel A, Karau R, Benali A, Faustmann PM, Juckel G, Petrasch-Parwez E. Acta Neuropathol. 2010 Jun;119(6):771-8

Progressive retinal atrophy in Schapendoes dogs: mutation of the newly identified CCDC66 gene.
Dekomien G, Vollrath C, Petrasch-Parwez E, Boevé MH, Akkad DA, Gerding WM, Epplen JT. Neurogenetics. 2010 May;11(2):163-74

2009

Unintended spread of a biosafety level 2 recombinant retrovirus.
Stang A, Petrasch-Parwez E, Brandt S, Dermietzel R, Meyer HE, Stühler K, Liffers ST, Uberla K, Grunwald T. Retrovirology. 2009 Sep 22;6:86

Variation in genes of the epidermal differentiation complex in German atopic dermatitis patients.
Stemmler S, Nothnagel M, Parwez Q, Petrasch-Parwez E, Epplen JT, Hoffjan S. Int J Immunogenet. 2009 Aug;36(4):217-22

Analysis of variation in the IL7RA and IL2RA genes in atopic dermatitis.
Hoffjan S, Beygo J, Akkad DA, Parwez Q, Petrasch-Parwez E, Epplen JT. J Dermatol Sci. 2009 Aug;55(2):138-40. No abstract available

Variation in the IL7RA and IL2RA genes in German multiple sclerosis patients.
Akkad DA, Hoffjan S, Petrasch-Parwez E, Beygo J, Gold R, Epplen JT. J Autoimmun. 2009 Mar;32(2):110-5

Spinocerebellar ataxia type 6 (SCA6): neurodegeneration goes beyond the known brain predilection sites. Gierga K, Schelhaas HJ, Brunt ER, Seidel K, Scherzed W, Egensperger R, de Vos RA, den Dunnen W, Ippel PF, Petrasch-Parwez E, Deller T, Schöls L, Rüb U. Neuropathol Appl Neurobiol. 2009 Oct;35(5):515-27

Variation in the BDNF and NGFB genes in German atopic dermatitis patients.
Hoffjan S, Parwez Q, Petrasch-Parwez E, Stemmler S. Mol Cell Probes. 2009 Feb;23(1):35-8

No evidence of an association between polymorphisms in the IRAK-M gene and atopic dermatitis in a German cohort. Beygo J, Parwez Q, Petrasch-Parwez E, Epplen JT, Hoffjan S. Mol Cell Probes. 2009 Feb;23(1)

2008

Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease. Nuber S, Petrasch-Parwez E, Winner B, Winkler J, von Hörsten S, Schmidt T, Boy J, Kuhn M, Nguyen HP, Teismann P, Schulz JB, Neumann M, Pichler BJ, Reischl G, Holzmann C, Schmitt I, Bornemann A, Kuhn W, Zimmermann F, Servadio A, Riess O. J Neurosci. 2008 Mar 5;28(10):2471-84

2007

Characterization of connexin31.1-deficient mice reveals impaired placental development.
Zheng-Fischhöfer Q, Kibschull M, Schnichels M, Kretz M, Petrasch-Parwez E, Strotmann J, Reucher H, Lynn BD, Nagy JI, Lye SJ, Winterhager E, Willecke K. Dev Biol. 2007 Dec 1;312(1):258-71

Polymorphisms in NACHT-LRR (NLR) genes in atopic dermatitis. Macaluso F, Nothnagel M, Parwez Q, Petrasch-Parwez E, Bechara FG, Epplen JT, Hoffjan S. Exp Dermatol. 2007 Aug;16(8):692-8.

Localization of the pannexin1 protein at postsynaptic sites in the cerebral cortex and hippocampus. Zoidl G, Petrasch-Parwez E, Ray A, Meier C, Bunse S, Habbes HW, Dahl G, Dermietzel R. Neuroscience. 2007 Apr 25;146(1):9-16

Association of toll-interacting protein gene polymorphisms with atopic dermatitis. Schimming TT, Parwez Q, Petrasch-Parwez E, Nothnagel M, Epplen JT, Hoffjan S. BMC Dermatol. 2007 Mar 16;7:3

Haplotype-defined linkage region for gPRA in Schapendoes dogs.
Lippmann T, Jonkisz A, Dobosz T, Petrasch-Parwez E, Epplen JT, Dekomien G.
Mol Vis. 2007 Feb 7;13:174-80

Cellular and subcellular localization of Huntingtin [corrected] aggregates in the brain of a rat transgenic for Huntington disease. Petrasch-Parwez E, Nguyen HP, Löbbecke-Schumacher M, Habbes HW, Wieczorek S, Riess O, Andres KH, Dermietzel R, Von Hörsten S. J Comp Neurol. 2007 Apr 10;501(5):716-30

Two common loss-of-function mutations within the filaggrin gene predispose for early onset of atopic dermatitis. Stemmler S, Parwez Q, Petrasch-Parwez E, Epplen JT, Hoffjan S. J Invest Dermatol. 2007 Mar;127(3):722-4.

Cellular and subcellular localization of paralemmin-1, a protein involved in cell shape control, in the rat brain, adrenal gland and kidney. Kutzleb C, Petrasch-Parwez E, Kilimann MW. Histochem Cell Biol. 2007 Jan;127(1):13-30

2006

Association screen for atopic dermatitis candidate gene regions using microsatellite markers in pooled DNA samples. Hoffjan S, Parwez Q, Petrasch-Parwez E, Falkenstein D, Nothnagel M, Epplen JT. Int J Immunogenet. 2006 Dec;33(6):401-9.

Degeneration of ingestion-related brainstem nuclei in spinocerebellar ataxia type 2, 3, 6 and 7.
Rüb U, Brunt ER, Petrasch-Parwez E, Schöls L, Theegarten D, Auburger G, Seidel K, Schultz C, Gierga K, Paulson H, van Broeckhoven C, Deller T, de Vos RA. Neuropathol Appl Neurobiol. 2006 Dec;32(6):635-49

Behavioral abnormalities precede neuropathological markers in rats transgenic for Huntington's disease. Nguyen HP, Kobbe P, Rahne H, Wörpel T, Jäger B, Stephan M, Pabst R, Holzmann C, Riess O, Korr H, Kántor O, Petrasch-Parwez E, Wetzel R, Osmand A, von Hörsten S. Hum Mol Genet. 2006 Nov 1;15(21):3177-94

2005

Molecular characterization and immunohistochemical localization of palmdelphin, a cytosolic isoform of the paralemmin protein family implicated in membrane dynamics. Hu B, Petrasch-Parwez E, Laue MM, Kilimann MW. Eur J Cell Biol. 2005 Nov;84(11):853-66

Is the retina affected in Huntington disease?
Petrasch-Parwez E, Saft C, Schlichting A, Andrich J, Napirei M, Arning L, Wieczorek S, Dermietzel R, Epplen JT. Acta Neuropathol. 2005 Nov;110(5):523-5

Evaluation of the toll-like receptor 6 Ser249Pro polymorphism in patients with asthma, atopic dermatitis and chronic obstructive pulmonary disease. Hoffjan S, Stemmler S, Parwez Q, Petrasch-Parwez E, Arinir U, Rohde G, Reinitz-Rademacher K, Schultze-Werninghaus G, Bufe A, Epplen JT.
BMC Med Genet. 2005 Sep 28;6:34

Loss of connexin36 increases retinal cell vulnerability to secondary cell loss. Striedinger K, Petrasch-Parwez E, Zoidl G, Napirei M, Meier C, Eysel UT, Dermietzel R. Eur J Neurosci. 2005 Aug;22(3):605-16

1998-2004

Fine-structural analysis and connexin expression in the retina of a transgenic model of Huntington's disease. Petrasch-Parwez E, Habbes HW, Weickert S, Löbbecke-Schumacher M, Striedinger K, Wieczorek S, Dermietzel R, Epplen JT. J Comp Neurol. 2004 Nov 8;479(2):181-97

Expression pattern of lacZ reporter gene representing connexin36 in transgenic mice.
Degen J, Meier C, Van Der Giessen RS, Söhl G, Petrasch-Parwez E, Urschel S, Dermietzel R, Schilling K, De Zeeuw CI, Willecke K. J Comp Neurol. 2004 Jun 7;473(4):511-25

Deformation of network connectivity in the inferior olive of connexin 36-deficient mice is compensated by morphological and electrophysiological changes at the single neuron level. De Zeeuw CI, Chorev E, Devor A, Manor Y, Van Der Giessen RS, De Jeu MT, Hoogenraad CC, Bijman J, Ruigrok TJ, French P, Jaarsma D, Kistler WM, Meier C, Petrasch-Parwez E, Dermietzel R, Sohl G, Gueldenagel M, Willecke K, Yarom Y. J Neurosci. 2003 Jun 1;23(11):4700-11

Evidence for a role of the N-terminal domain in subcellular localization of the neuronal connexin36 (Cx36). Zoidl G, Meier C, Petrasch-Parwez E, Zoidl C, Habbes HW, Kremer M, Srinivas M, Spray DC, Dermietzel R. J Neurosci Res. 2002 Aug 15;69(4):448-65

Immunohistochemical detection of the neuronal connexin36 in the mouse central nervous system in comparison to connexin36-deficient tissues. Meier C, Petrasch-Parwez E, Habbes HW, Teubner B, Güldenagel M, Degen J, Söhl G, Willecke K, Dermietzel R. Histochem Cell Biol. 2002 Jun;117(6):461-71

Axo-axonal coupling. a novel mechanism for ultrafast neuronal communication. Schmitz D, Schuchmann S, Fisahn A, Draguhn A, Buhl EH, Petrasch-Parwez E, Dermietzel R, Heinemann U, Traub RD. Neuron. 2001

Functional expression of the murine connexin 36 gene coding for a neuron-specific gap junctional protein. Teubner B, Degen J, Söhl G, Güldenagel M, Bukauskas FF, Trexler EB, Verselis VK, De Zeeuw CI, Lee CG, Kozak CA, Petrasch-Parwez E, Dermietzel R, Willecke K. J Membr Biol. 2000 Aug 1;176(3):249-62

Neurobeachin: A protein kinase A-anchoring, beige/Chediak-higashi protein homolog implicated in neuronal membrane traffic. Wang X, Herberg FW, Laue MM, Wullner C, Hu B, Petrasch-Parwez E, Kilimann MW. J Neurosci. 2000 Dec 1;20(23):8551-65

Aczonin, a 550-kD putative scaffolding protein of presynaptic active zones, shares homology regions with Rim and Bassoon and binds profilin. Wang X, Kibschull M, Laue MM, Lichte B, Petrasch-Parwez E, Kilimann MW. J Cell Biol. 1999 Oct 4;147(1):151-62

Paralemmin, a prenyl-palmitoyl-anchored phosphoprotein abundant in neurons and implicated in plasma membrane dynamics and cell process formation. Kutzleb C, Sanders G, Yamamoto R, Wang X, Lichte B, Petrasch-Parwez E, Kilimann MW. J Cell Biol. 1998 Nov 2;143(3):795-813