Neural Dynamics Underlies Functions of the Brain

When we think, memorize or recall, thousands of neurons are active in our brain. This activity changes rapidly with time, hence the activity is dynamic. Our question is how this activity of neurons is coordinated to generate these functions.

In our lab, we utilize two different methods to achieve this goal. One is in-vitro electrophysiology where we observe neural activity from individual live neurons. The other is computational modeling where we test how neural activity can contribute to brain function using computer simulation. By combining these two methods, we try to understand how neural activity contribute to brain functions.
We currently focus on functions of the medial temporal lobe which is crucial for learning and memory. After years of study, it still remains unclear how individual neuronal activity is coordinated to support learning and memory in this region. The figure above describes two examples of recent research we conducted in the medial temporal lobe.