The research unit “Medical Bioinformatics” is coordinated by PD Dr. Martin Eisenacher and links the applied proteomics activities of the other research units of the MPC and the theoretic Bioinformatics / Biostatistics.
Besides infrastructural responsibilities for the MPC (e.g., server-virtualization system providing numerous data analysis servers and databases, high performance compute cluster and archiving und backup solutions) the unit consists of two working groups (WGs) “Algorithmic Proteomics” and “Expression Profiling”. They conduct their own research and develop new methods, algorithms, analysis workflows and software for statistically valid analysis of proteomics data. In the “Protein Unit for Research in Europe“ (PURE) which is funded by the German state NRW the WGs analyse data arising from several different clinical sources and technological platforms. The aim of this project is to identify and validate biomarkers for neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease as well as different types of cancer such as bladder and pancreatic cancer.
The research unit “Medical Bioinformatics” was in the past involved in the preperation phase of a pan-European project for the sustainable establishment of infrastructure for information processing: „European Life Sciences Infrastructure for Biological Information (ELIXIR)“ as a part of the „European Strategy Forum on Research Infrastructures (ESFRI)“. In early summer 2014 the research unit was involved in the conception phase of the BMBF-funded German network for bioinformatics infrastructure (de.NBI), which started in march 2015 (see here).