Ausgewählte Publikationen - selected publications

Hou, X., Hagemann, N., Schoebel, S., Blankenfeldt, W., Goody, R.S., Erdmann, K.S.*,  Itzen, A.* A structural basis for Lowe syndrome caused by mutations in the Rab binding domain of OCRL1, EMBO J., 30, 1659-1670 (2011) *corresponding authors

Kock G., Dicks M., Heumann R., Erdmann K.S., Stoll R. Sequence-specific (1)H, (13)C, and (15)N assignment of the extended PDZ3 domain of the protein tyrosine phosphatase basophil-like PTP-BL. Biomol. NMR Assign. 4, 199–202 ( 2010)

Stenzel, N., Fetzer, C.P., Heumann, R., and Erdmann, K.S.. PDZ-domain-directed basolateral targeting of the peripheral membrane protein FRMPD2 in epithelial cells. J. Cell Sci., 122, 3374-3384 (2009)

Mao, Y., Balkin, D.M., Zoncu, R., Erdmann, K.S., Tomasini, L., Hu, F., Jin, M.M., Hodson, M.E., and De Camilli, P.. A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism. EMBO J., 28, 1831-1842 (2009)

Welters, H.J., Oknianska, A., Erdmann, K.S., Ryffel, G., and Morgan, N.. The protein tyrosine phosphatase, PTP-BL, modulates pancreatic beta-cell proliferation by interaction with the Wnt signalling pathway. J. Endocrinol., 197, 543-552 (2008)

Stenzel, N, and Erdmann, K.S.. PDZ Domänen - Molekularer Baukasten der Natur. Bioforum, 5, 25-27 (2008)

Erdmann, K.S., Mao, Y., McCrea, H.J., Zoncu, R., Lee, S.Y., Summer, P., Modregger, J., Biemesderfer, D., Toomre, D., and De Camilli, P.. A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway. Dev. Cell, 13, 377-390 (2007)

Itoh, T., Erdmann, K.S., Roux, A., Habermann, B., Werner, H., and De Camilli, P.. Dynamin and the actin cytoskeleton cooperatively regulate plasma membrane invagination by BAR and F-BAR proteins. Dev. Cell, 9, 791-804 (2005)

Hartmann, M., Brigadski, T., Erdmann, K.S., Holtmann, B., Sendtner, M., Narz, F., and Lessmann, V.. Truncated TrkB receptor-induced outgrowth of dendritic filopodia involves the p75 neurotrophin receptor. J. Cell Sci. 117, 5803-5814 (2004)

Erdmann, K.S.. The Protein Tyrosine Phosphatase PTP-Basophile/Basophile-like: Interacting Proteins and Molecular Functions Eur. J. Biochem. 270, 4789-4798 (2003)

Kachel, N*., Erdmann, K.S.*, Kremer, W., Wolff, P., Gronwald, W., Heumann, R., and Kalbitzer, H.R.. Structure determination and ligand interactions of the PDZ2b domain of PTP-Bas (hPTP1E): Splicing induced modulation of ligand specificity. J. Mol. Biol. 334, 143-155 (2003)

Herrmann, L., Dittmar, T., and Erdmann, K.S.. The Protein Tyrosine Phosphatase PTP-BL associates with the Midbody and is involved in the Regulation of Cytokinesis. Mol. Biol. Cell 14, 230-240 (2003)

Palmer, A., Zimmer, M., Erdmann, K.S., Eulenburg, V., Porthin, A., Heumann, R., Deutsch, U., and Klein, R.. EphrinB phosphorylation and reverse signaling: regulation by Src kinases and PTP-BL phosphatase. Mol. Cell, 9, 725-737 (2002)

Klau, M., Hartmann, M., Erdmann, K.S., Heumann, R., and Lessmann, V.. Reduced number of functional synapses in hippocampal neurons overexpressing full-length TrkB receptors. J. Neurosci. Res. 66, 327-336 (2001)

Schultze, W., Eulenburg, V., Lessmann, V., Herrmann, L., Dittmar, T., Gundelfinger E.D., Heumann, R., and Erdmann, K.S.. The semaphorin Sema4F interacts with the synaptic associated protein SAP90/PSD-95. J. Neurochem. 78, 482-489 (2001)

Gross, C., Heumann, R., and Erdmann, K.S The protein kinase C-related kinase PRK2 interacts with the protein tyrosine phosphatase PTP-BL via a novel PDZ domain binding motif. FEBS Lett. 496, 101-104 (2001)

Erdmann, K.S., Kuhlmann, J., Lessmann, V., Herrmann, L., Eulenburg, V., Muller, O., and Heumann, R. The Adenomatous Polyposis Coli-protein (APC) interacts with the protein tyrosine phosphatase PTP-BL via an alternatively spliced PDZ domain. Oncogene, 19, 3894-3901 (2000)