Welcome to Biomolecular NMR at RUB
Biochemistry seeks to understand life at a molecular level by examining the relationship between the structure and function of biomolecules, in particular proteins, nucleic acids and lipids. To achieve this, we use techniques such as Biomolecular NMR Spectroscopy to determine the three-dimensional structures and dynamics of biomolecules as well as how they interact with each other and other molecules in solution at near-physiological conditions.
Our research focuses in the main on medically-relevant proteins, specifically those involved in the development of cancerous tumours, in order to better understand the causes of the condition and propose more effective treatment strategies. Examples include oncogenic proteins, tumour suppressors as well as proteins involved in malignant melanoma, to name but a few.
Other current areas of investigation cover the structure, function, dynamics and interaction of proteins associated with the transduction of physiological signals.